EVALUATING THE ROLE OF OMEGA 3 ON THE SIDE EFFECTS OF ISOTRETINOIN IN PATIENTS WITH THE ACNEA VULGARIS

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MIRNEZAMI MINA

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Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2017 | Volume:19 | Issue:10 (115) Page(s): 81-87

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Title

EVALUATING THE ROLE OF OMEGA 3 ON THE SIDE EFFECTS OF ISOTRETINOIN IN PATIENTS WITH THE ACNEA VULGARIS

Author(s)

MIRNEZAMI MINA | Issue Writer Certificate

Keywords

ACNE VULGARISQ2

ISOTRETINOINQ1

OMEGA 3Q1

Abstract

Background: ACNE VULGARIS is chronic inflamatory disease of the pilosebaceous unit.Patients experience psychological burdens like depression, anxiety, and low self- esteem. ISOTRETINOIN is used in the treatment of severe and recalcitrant acne; however, this treatment is associated with a number of partialy common adverse effects that it sometimes may stop the process of treatment. The aim of this study is to evaluate the effect of oral OMEGA 3 on sideeffects of ISOTRETINOIN.Materials and Methods: One hundred eighteen patients with severe ACNE VULGARIS were randomly divided into two groups. Control group received ISOTRETINOIN (0.5 mg/kg) alone and case group received ISOTRETINOIN (0.5 mg∕kg) combined with OMEGA 3 (2 capsuls) daily. The duration of treatment was 16 weeks.Mucocutaneous side- effects were assessed in patients(4, 8, 12, 16th wk).Results: Lip dryness (4, 8, 12th wk) and dryness of nose, skin, eye in the 4 th week in the patients with ACNE VULGARIS treated with ISOTRETINOIN and omega3 was lesser than in the patients treated with ISOTRETINOIN alone, that this difference was statistically significant (p<0.001).Conclusion: Based on the results of this study, OMEGA 3 decreased the mucocutaneous side effects in the patients with ACNE VULGARIS who received ISOTRETINOIN.

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APA: Copy

MIRNEZAMI, MINA. (2017). EVALUATING THE ROLE OF OMEGA 3 ON THE SIDE EFFECTS OF ISOTRETINOIN IN PATIENTS WITH THE ACNEA VULGARIS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 19(10 (115)), 81-87. SID. https://sid.ir/paper/68928/en

Vancouver: Copy

MIRNEZAMI MINA. EVALUATING THE ROLE OF OMEGA 3 ON THE SIDE EFFECTS OF ISOTRETINOIN IN PATIENTS WITH THE ACNEA VULGARIS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2017;19(10 (115)):81-87. Available from: https://sid.ir/paper/68928/en

IEEE: Copy

MINA MIRNEZAMI, “EVALUATING THE ROLE OF OMEGA 3 ON THE SIDE EFFECTS OF ISOTRETINOIN IN PATIENTS WITH THE ACNEA VULGARIS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 19, no. 10 (115), pp. 81–87, 2017, [Online]. Available: https://sid.ir/paper/68928/en

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