DETERMINATION OF EXTRACTION AND ANALYSIS METHOD FOR IMIPENEM IN HOSPITAL SEWAGE SAMPLES USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-UV DETECTOR AND WITH SOLID PHASE EXTRACTION COLUMN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DEHGHANZADEH REIHANI M.; SAFAVY N.; GHAEMMAGHAMI HAZAVEH J.; POURAKBAR M.; NAZARI SH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2014 | Volume:17 | Issue:6 (87) Page(s): 9-18

Download Full-Text

Persian Verion

View:

1,026

Download:

Cites:

Information Journal Paper

Title

DETERMINATION OF EXTRACTION AND ANALYSIS METHOD FOR IMIPENEM IN HOSPITAL SEWAGE SAMPLES USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-UV DETECTOR AND WITH SOLID PHASE EXTRACTION COLUMN

Author(s)

Keywords

IMIPENEMQ2

ANTIBIOTICQ2

HOSPITAL WASTEWATERQ2

HPLCQ2

SPE EXTRACTIONQ2

Abstract

Background: Drugs residual discharge into the environment through municipal and HOSPITAL WASTEWATERs is one of the emergent environmental problems. IMIPENEM as a professional hospital ANTIBIOTIC is widely used against gram- positive and negative bacteria and with entrance to the aquatic environments could prompt a lot of risks such as bacteria resistance, allergies, spoiling alga and daphnia and interrupting in wastewater treatment processes. Therefore there is a command to develop a method for extraction and determination of IMIPENEM from hospital sewage.Materials and Methods: Solid phase extraction (SPE) was used to extract IMIPENEM from samples. Recovery percentage calculated at different pH of 3 and 7. The extracted samples analyzed by High Performance Liquid Chromatography (HPLC) equipped with UV detector. HPLC operated using borate buffer/methanol as mobile phase at flow rate of 0.7 ml/min, column temperature of 20 °C, and UV wavelength of 280-300 nm.Results: Maximum recovery percentage was obtained 68% at pH=7. The best condition for HPLC was 80: 20 ratio of borate buffer/methanol with pH=7.5 and at UV wavelength of 300 nm.Linearity calculated 0.9829, primary and intermediate precision both were more than 95%. Limit of detection (LOD) and limit of quantification (LOQ) were 3 and 10 mg/l respectively.Conclusion: The method could simply and with significant reliability be applied to extract and determinate IMIPENEM in complex HOSPITAL WASTEWATER matrixes.

Cites

No record.

References

Cite

APA: Copy

DEHGHANZADEH REIHANI, M., SAFAVY, N., GHAEMMAGHAMI HAZAVEH, J., POURAKBAR, M., & NAZARI, SH.. (2014). DETERMINATION OF EXTRACTION AND ANALYSIS METHOD FOR IMIPENEM IN HOSPITAL SEWAGE SAMPLES USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-UV DETECTOR AND WITH SOLID PHASE EXTRACTION COLUMN. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 17(6 (87)), 9-18. SID. https://sid.ir/paper/69358/en

Vancouver: Copy

DEHGHANZADEH REIHANI M., SAFAVY N., GHAEMMAGHAMI HAZAVEH J., POURAKBAR M., NAZARI SH.. DETERMINATION OF EXTRACTION AND ANALYSIS METHOD FOR IMIPENEM IN HOSPITAL SEWAGE SAMPLES USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-UV DETECTOR AND WITH SOLID PHASE EXTRACTION COLUMN. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2014;17(6 (87)):9-18. Available from: https://sid.ir/paper/69358/en

IEEE: Copy

M. DEHGHANZADEH REIHANI, N. SAFAVY, J. GHAEMMAGHAMI HAZAVEH, M. POURAKBAR, and SH. NAZARI, “DETERMINATION OF EXTRACTION AND ANALYSIS METHOD FOR IMIPENEM IN HOSPITAL SEWAGE SAMPLES USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-UV DETECTOR AND WITH SOLID PHASE EXTRACTION COLUMN,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 17, no. 6 (87), pp. 9–18, 2014, [Online]. Available: https://sid.ir/paper/69358/en

Related Journal Papers