مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

1

Information Journal Paper

Title

EFFICACY OF HUMAN UMBILICAL STEM CELLS CULTURED ON POLYLACTIC/ POLYGLYCOLIC ACID MEMBRANE IN THE TREATMENT OF MULTIPLE GINGIVAL RECESSION DEFECTS: A RANDOMIZED CONTROLLED CLINICAL STUDY

Pages

  95-103

Abstract

 Statement of the Problem: Recently allogenic mesenchymal STEM CELLS are proposed to have multipotential progenitor cell capabilities to differentiate into cementoblasts, osteoblasts, and periodontal ligament fibroblasts.Purpose: The aim of the present study was to compare the efficacy of human umbili-cal STEM CELLS cultured on polylactic acid (PLA), polyglycolic acid (PGA) membrane with PLA/PGA MEMBRANE alone in the treatment of multiple GINGIVAL RECESSION de-fects.Materials and Method: A total number of 14 cases of multiple GINGIVAL RECESSION (Miller’s Class I or II) located in the anterior region were randomly selected and divid-ed into test (stem cells in combination with PLA/PGA MEMBRANE) and control group (PLA/PGA MEMBRANE alone). Clinical parameters including GINGIVAL RECESSION, prob-ing pocket depth, clinical attachment level, and width of keratinized gingiva were rec-orded at baseline, and at 6 months postoperative.Results: At baseline, there was 2.28 mm and 2.14mm mean GINGIVAL RECESSION at 16 sites and 14 sites in test and control groups respectively. At 6 months post-surgery, test group showed 1.57 mm mean reduction of GINGIVAL RECESSION indicating 66% root coverage, while the control group showed 1.24mm mean reduction of gingival reces-sion indicating 57% root coverage.Conclusion: In the present study, the stem cell with PLA/PGA MEMBRANE showed significantly higher mean root coverage compared to only PLA/PGA MEMBRANE group.

Cites

References

Cite

APA: Copy

ZANWAR, KUSHAL, GANJI, KIRAN KUMAR, & BHONGADE, MANOHAR L.. (2017). EFFICACY OF HUMAN UMBILICAL STEM CELLS CULTURED ON POLYLACTIC/ POLYGLYCOLIC ACID MEMBRANE IN THE TREATMENT OF MULTIPLE GINGIVAL RECESSION DEFECTS: A RANDOMIZED CONTROLLED CLINICAL STUDY. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), 18(2), 95-103. SID. https://sid.ir/paper/700135/en

Vancouver: Copy

ZANWAR KUSHAL, GANJI KIRAN KUMAR, BHONGADE MANOHAR L.. EFFICACY OF HUMAN UMBILICAL STEM CELLS CULTURED ON POLYLACTIC/ POLYGLYCOLIC ACID MEMBRANE IN THE TREATMENT OF MULTIPLE GINGIVAL RECESSION DEFECTS: A RANDOMIZED CONTROLLED CLINICAL STUDY. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2017;18(2):95-103. Available from: https://sid.ir/paper/700135/en

IEEE: Copy

KUSHAL ZANWAR, KIRAN KUMAR GANJI, and MANOHAR L. BHONGADE, “EFFICACY OF HUMAN UMBILICAL STEM CELLS CULTURED ON POLYLACTIC/ POLYGLYCOLIC ACID MEMBRANE IN THE TREATMENT OF MULTIPLE GINGIVAL RECESSION DEFECTS: A RANDOMIZED CONTROLLED CLINICAL STUDY,” JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), vol. 18, no. 2, pp. 95–103, 2017, [Online]. Available: https://sid.ir/paper/700135/en

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