مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

217
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

THE RELATIONSHIP OF FOK1 AND BSMI POLYMORPHISMS WITH VITAMIN D ON WOMEN’S BREAST CANCER IN URMIA

Pages

  753-761

Abstract

 Background & Aims: BREAST CANCER is one of the most common cancers worldwide and accounts for one third of all cancers in women. VITAMIN D and its metabolites have a critical role in bone metabolism and any decrease in synthesis and production of this vitamin causes cancers, including breast and ovarian and colon. In this study, we examined the relationship between FOK1 and BSMI restriction enzymes dealing with BREAST CANCER.Materials & Methods: This study was conducted on 180 women (90 female patients and 90 healthy women). DNA was extracted using salting out method. In the next stage the designed primers were connected to complementary sequences using PCR and in the last stage, restriction enzymes specific places on the DNA sequences were cut using RFLP. Finally the data were analyzed using SPSSV23, chi-square and t-Test.Results: There was no significant difference considering the density of the obtained genotype POLYMORPHISMs in both patients and controls (P =0.422). There was a significant difference between the genotypes considering age (P=0.19) and slow the disease progression (P=0.65). In both groups, there was significant association between the variables of age, breastfeeding and age at first pregnancy (p<0.05). There also was association between the use of oral contraceptives with occurrences of the disease (p>0.005).Conclusion: In view of the role of VITAMIN D receptors in cell cycle control cycles and the whole immune system in BREAST CANCER need to consider other gene POLYMORPHISMs with BREAST CANCER is suggested.

Cites

  • No record.
  • References

  • No record.
  • Cite

    APA: Copy

    TALANEH, SASAN, GHAVAM, FAROKH, MOGHEYSI, EBRAHIM, & ESNAASHARI, OMID. (2016). THE RELATIONSHIP OF FOK1 AND BSMI POLYMORPHISMS WITH VITAMIN D ON WOMEN’S BREAST CANCER IN URMIA. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 27(9), 753-761. SID. https://sid.ir/paper/703898/en

    Vancouver: Copy

    TALANEH SASAN, GHAVAM FAROKH, MOGHEYSI EBRAHIM, ESNAASHARI OMID. THE RELATIONSHIP OF FOK1 AND BSMI POLYMORPHISMS WITH VITAMIN D ON WOMEN’S BREAST CANCER IN URMIA. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2016;27(9):753-761. Available from: https://sid.ir/paper/703898/en

    IEEE: Copy

    SASAN TALANEH, FAROKH GHAVAM, EBRAHIM MOGHEYSI, and OMID ESNAASHARI, “THE RELATIONSHIP OF FOK1 AND BSMI POLYMORPHISMS WITH VITAMIN D ON WOMEN’S BREAST CANCER IN URMIA,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 27, no. 9, pp. 753–761, 2016, [Online]. Available: https://sid.ir/paper/703898/en

    Related Journal Papers

  • No record.
  • Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops






    مرکز اطلاعات علمی SID
    strs
    دانشگاه امام حسین
    بنیاد ملی بازیهای رایانه ای
    کلید پژوه
    ایران سرچ
    ایران سرچ
    File Not Exists.
    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button