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Information Journal Paper

Title

Antioxidant Property and Bactericidal Activity of Linum usitatissimum Seed Essential Oil Nanoemulsion (LSEO-NE) on Staphylococcus aureus

Pages

  0-0

Keywords

Linum usitatissimum Seed Essential Oil (LSEO) 

Abstract

 Background: Linum usitatissimum Seed Essential Oil (LSEO) as an efficient antimicrobial compound contains various types of phytochemicals, such as lignans and phenols. Objectives: In the current study, we produced LSEO nanoemulsion (LSEO-NE) to study its Antioxidant capacity and bactericidal activity against Staphylococcus aureus. Methods: The LSEO-NE was produced using the ultrasonication method and characterized by Atomic Force Microscopy (AFM), Dynamic Light Scattering (DLS), and Scanning Electron Microscopy (SEM). Then, we measured its Antioxidant activity utilizing both ABTS and DPPH tests at four different LSEO-NE concentrations (200, 600, 800, and 1000  g/mL) compared to glutathione. Finally, we evaluated its bactericidal activity on S. aureus by studying Antibiotic Susceptibility Testing (AST) using LSEO-NE-smeared discs compared to non-smeared and kanamycin discs. Results: The 67. 3 nm droplets of LSEO-NE with PDI of 0. 452 exhibited strong Antioxidant activity, similar to glutathione, in both ABTS (IC50 = 350  g/mL) and DPPH (IC50 = 235  g/mL) tests. Moreover, the AST results revealed the significant sensitivity of S. aureus to LSEO-NE-smeared discs when compared to non-smeared and kanamycin discs. Conclusions: According to the results, LSEO-NE can be applied as a safe, natural, and effective antibiotic for bacterial infections caused by S. aureus in most organs, such as the respiratory system and skin. However, further in vivo studies are required to evaluate the LSEO-NE antibacterial efficiency against other pathogenic S. aureus strains.

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    APA: Copy

    Keykhasalar, Roghaye, HOMAYOUNI TABRIZI, MASOUD, & ARDALAN, POURAN. (2020). Antioxidant Property and Bactericidal Activity of Linum usitatissimum Seed Essential Oil Nanoemulsion (LSEO-NE) on Staphylococcus aureus. INTERNATIONAL JOURNAL OF INFECTION, 7(2), 0-0. SID. https://sid.ir/paper/705693/en

    Vancouver: Copy

    Keykhasalar Roghaye, HOMAYOUNI TABRIZI MASOUD, ARDALAN POURAN. Antioxidant Property and Bactericidal Activity of Linum usitatissimum Seed Essential Oil Nanoemulsion (LSEO-NE) on Staphylococcus aureus. INTERNATIONAL JOURNAL OF INFECTION[Internet]. 2020;7(2):0-0. Available from: https://sid.ir/paper/705693/en

    IEEE: Copy

    Roghaye Keykhasalar, MASOUD HOMAYOUNI TABRIZI, and POURAN ARDALAN, “Antioxidant Property and Bactericidal Activity of Linum usitatissimum Seed Essential Oil Nanoemulsion (LSEO-NE) on Staphylococcus aureus,” INTERNATIONAL JOURNAL OF INFECTION, vol. 7, no. 2, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/705693/en

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