COMPARISON OF BETA-2 MICROGLOBULIN LEVEL AND SOME VARIABLES BETWEEN THALASSEMIA MAJOR PATIENTS WHO TREATED BY DESFERAL AND CONTROL GROUP

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ZAFARI MANDANA; AGHA MOHAMMADI AZAR

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Journal: Zahedan Journal of Research in Medical Sciences Year:2017 | Volume:19 | Issue:10 Page(s): 0-0

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Title

COMPARISON OF BETA-2 MICROGLOBULIN LEVEL AND SOME VARIABLES BETWEEN THALASSEMIA MAJOR PATIENTS WHO TREATED BY DESFERAL AND CONTROL GROUP

Author(s)

ZAFARI MANDANA | AGHA MOHAMMADI AZAR | Issue Writer Certificate

Keywords

TRANSFUSION DEPENDENT THALASSEMIA MAJOR

DESFERAL

β2 MICROGLOBULIN

Abstract

Background: Iron over load will be appearing in kidney following blood transfusion. DESFERAL as an iron chelator can be ended renal complication.Objectives: The aimof this study is evaluation the level of b2 microglobulin in b - Thalassemia major patients for followupproximal tubular damage.Methods: In this descriptive and analytic study 40 thalassemic patients who were treated by DESFERAL and 40 healthy subjects enrolled in this study randomly. For evaluation the proximal tubular damage in these groups, we measured the b -2 microglobin.Another variable such as: Ca, Mg, P and Urea of blood and K, Cr, protein and volume of urine 24 hours were measured. We compared these variables between two groups. And descriptive and analytic analyses were used.Results: The level of b 2 microglobulin had significant difference in both groups, also the level of Ca, K and b -2 Globin in serum and Cr, protein and urine volume in 24 houres had significant difference.Conclusions: The higher level of b 2microglobulin in Thalassemia major patient who were treated by DESFERAL, show the proximal tubular damage.

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APA: Copy

ZAFARI, MANDANA, & AGHA MOHAMMADI, AZAR. (). . , (), -. SID. https://sid.ir/paper/708393/en

Vancouver: Copy

ZAFARI MANDANA, AGHA MOHAMMADI AZAR. . [Internet]. ;():-. Available from: https://sid.ir/paper/708393/en

IEEE: Copy

MANDANA ZAFARI, and AZAR AGHA MOHAMMADI, “,” , vol. , no. , pp. –, , [Online]. Available: https://sid.ir/paper/708393/en

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