مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

145
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

131
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Ameliorative effect of berberine on functional disorders and histological damages of pancreas in renal ischemia/reperfusion

Pages

  123-128

Abstract

 Introduction: Renal ischemia/reperfusion (RIR) is considered as one of the most prevalent reasons of acute renal failure. As renal failure is progressed, renal gluconeogenesis and insulin clearance are decreased. Berberine is the most important alkaloid of Berberis vulgaris. It has anti-diabetic, anti-inflammatory and antimicrobial properties. The goal of this study was to assign the effect of RIR on the Pancreas and to define the effect of Berberine on the pancreatic damages induced by RIR. Methods: Male rats were allocated into four groups (n=7): sham (no intervention), Ber (Berberine, 15mg/kg/day), I/R (subjected to 45min bilateral renal artery occlusion), Ber+I/R (Berberine, 15mg/kg/day). After 24h, blood samples were collected for biochemical analysis and eventually Pancreas tissue samples were kept for subsequent histological examination. Results: The ischemic challenge of kidneys resulted in pancreatic vascular congestion, which was associated with decreased plasma level of glucose as well as increased plasma insulin, creatinine and blood urea nitrogen levels at the termination of reperfusion period. In Ber+I/R group, pancreatic vascular congestion and decreased plasma level of insulin were improved concomitant to increase in plasma creatinine and urea nitrogen being smaller than those of the non-treated rats. Conclusion: RIR injury has some roles in the development of tissue damages and probably functional disorders of the Pancreas in rats. Furthermore, Berberine has an ameliorative effect against organ injury induced by RIR in rat.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    Gholampour, Firouzeh, & Mansouri, Sareh. (2019). Ameliorative effect of berberine on functional disorders and histological damages of pancreas in renal ischemia/reperfusion. PHYSIOLOGY AND PHARMACOLOGY, 23(2), 123-128. SID. https://sid.ir/paper/740473/en

    Vancouver: Copy

    Gholampour Firouzeh, Mansouri Sareh. Ameliorative effect of berberine on functional disorders and histological damages of pancreas in renal ischemia/reperfusion. PHYSIOLOGY AND PHARMACOLOGY[Internet]. 2019;23(2):123-128. Available from: https://sid.ir/paper/740473/en

    IEEE: Copy

    Firouzeh Gholampour, and Sareh Mansouri, “Ameliorative effect of berberine on functional disorders and histological damages of pancreas in renal ischemia/reperfusion,” PHYSIOLOGY AND PHARMACOLOGY, vol. 23, no. 2, pp. 123–128, 2019, [Online]. Available: https://sid.ir/paper/740473/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button