EFFECT OF ARTEMISIA ABSINTHIUM ON ELECTROPHYSIOLOGICAL PROPERTIES OF ISOLATED HEART OF RATS

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KHOURI V.; NAYEBPOUR M.

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Journal: Physiology and Pharmacology Year:2007 | Volume:10 | Issue:4 Page(s): 303-311

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Information Journal Paper

Title

EFFECT OF ARTEMISIA ABSINTHIUM ON ELECTROPHYSIOLOGICAL PROPERTIES OF ISOLATED HEART OF RATS

Author(s)

KHOURI V. | NAYEBPOUR M. | Issue Writer Certificate

Keywords

ARTEMISIA ABSINTHIUMQ3

ARRHYTHMIAQ3

LANGENDORFFQ3

ELECTROPHYSIOLOGYQ3

HEARTQ3

Abstract

Introduction: Treatment of supraventricular ARRHYTHMIA includes wide range of medical interventions. Herbal remedies are suitable alternatives for synthetic drugs due to their availability, minimal side effects and lower price. Pharmacological studies and traditional medical literature point to the cardiovascular effects of the ARTEMISIA ABSINTHIUM L. from Compositae family of plants.Methods: In the present study we used LANGENDORFF model of isolated HEART of rats as an experimental model to determine the effect of various concentrations of methanolic extract of A. absinthium (3×10 -11 %W/V to 4× 10 -8 %W/V) on electrophysiological properties of isolated HEARTs.Results: Our results showed depressant effect of A. absinthium extract on Wenchebach Cycle Length (WBCL), AV Conduction Time (AVCT), Effective and Functional Refractory Periods (ERP & FRP) of the isolated HEART.Conclusion: The results indicated potential antiarrhythmic effect of A. absinthium extract in treating supraventricular tachyarrhythmia.

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APA: Copy

KHOURI, V., & NAYEBPOUR, M.. (2007). EFFECT OF ARTEMISIA ABSINTHIUM ON ELECTROPHYSIOLOGICAL PROPERTIES OF ISOLATED HEART OF RATS. PHYSIOLOGY AND PHARMACOLOGY, 10(4), 303-311. SID. https://sid.ir/paper/74963/en

Vancouver: Copy

KHOURI V., NAYEBPOUR M.. EFFECT OF ARTEMISIA ABSINTHIUM ON ELECTROPHYSIOLOGICAL PROPERTIES OF ISOLATED HEART OF RATS. PHYSIOLOGY AND PHARMACOLOGY[Internet]. 2007;10(4):303-311. Available from: https://sid.ir/paper/74963/en

IEEE: Copy

V. KHOURI, and M. NAYEBPOUR, “EFFECT OF ARTEMISIA ABSINTHIUM ON ELECTROPHYSIOLOGICAL PROPERTIES OF ISOLATED HEART OF RATS,” PHYSIOLOGY AND PHARMACOLOGY, vol. 10, no. 4, pp. 303–311, 2007, [Online]. Available: https://sid.ir/paper/74963/en

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