Hypoxic-ischemic encephalopathy in a young man due to tramadol overdose

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ATAEE ZAHRA; DADPOUR BITA

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Journal Paper

Paper Information

Journal: JOURNAL OF EMERGENCY PRACTICE AND TRAUMA Year:2020 | Volume:6 | Issue:2 Page(s): 112-114

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Information Journal Paper

Title

Hypoxic-ischemic encephalopathy in a young man due to tramadol overdose

Author(s)

ATAEE ZAHRA | DADPOUR BITA | Issue Writer Certificate

Keywords

Tramadol

Status epilepticus

Hypoxic ischemic encephalopathy

Antiepileptic

Abstract

Objective: Tramadol is a synthetic analgesic with two mechanisms. The opioid and non-opioid mechanisms are responsible for Tramadol side effects. Non-opioid side effects of Tramadol are due to the reuptake inhibitions of serotonin and norepinephrine. Some of the side effects include anaphylactoid reactions, CNS depression, hypoglycemia, hypotension, respiratory depression, seizures, and serotonin syndrome. Seizure may happen in therapeutic doses. If the frequency of Tramadol seizures increases, ischemic brain injury and hypoxic-ischemic encephalopathy can be induced. Case Report: We report a young man with a history of Tramadol abuse that was admitted with Status epilepticus in Imam Reza hospital in Mashhad, Iran. Due to his altered mental status, he was intubated and Antiepileptic agents were prescribed. He was transferred to ICU. After regaining consciousness, he was extubated and with the prescription of rehabilitation support he was discharged. Conclusion: Tramadol is a synthetic analgesic agent with less potential for dependence. It is important to mention that the overdose of this drug is common. This drug has two mechanisms. This paper reports a case that developed generalized tonic clonic seizures due to Tramadol and Hypoxic ischemic encephalopathy. With adequate treatment and supportive care, patient’ s mental status improves and he/she can be discharged.

Cites

A Review on Complications of Tramadol Overdose

References

Comparative analysis of opioid queries on erowid. org: an opportunity to advance harm reduction

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APA: Copy

ATAEE, ZAHRA, & DADPOUR, BITA. (2020). Hypoxic-ischemic encephalopathy in a young man due to tramadol overdose. JOURNAL OF EMERGENCY PRACTICE AND TRAUMA, 6(2), 112-114. SID. https://sid.ir/paper/765397/en

Vancouver: Copy

ATAEE ZAHRA, DADPOUR BITA. Hypoxic-ischemic encephalopathy in a young man due to tramadol overdose. JOURNAL OF EMERGENCY PRACTICE AND TRAUMA[Internet]. 2020;6(2):112-114. Available from: https://sid.ir/paper/765397/en

IEEE: Copy

ZAHRA ATAEE, and BITA DADPOUR, “Hypoxic-ischemic encephalopathy in a young man due to tramadol overdose,” JOURNAL OF EMERGENCY PRACTICE AND TRAUMA, vol. 6, no. 2, pp. 112–114, 2020, [Online]. Available: https://sid.ir/paper/765397/en

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