Anti-inflammatory properties of enamel matrix derivative on non-surgical management of periimplant mucosal inflammation

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POURABBAS REZA; KASHEFIMEHR ATABAK; Moradi Aouzar

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Journal Paper

Paper Information

Journal: JOURNAL OF ADVANCED PERIODONTOLOGY AND IMPLANT DENTISTRY Year:2019 | Volume:11 | Issue:suppl A (19th international congress of Iranian Academy of Periodontology) Page(s): 0-0

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Information Journal Paper

Title

Anti-inflammatory properties of enamel matrix derivative on non-surgical management of periimplant mucosal inflammation

Author(s)

POURABBAS REZA | KASHEFIMEHR ATABAK | Moradi Aouzar

Keywords

Cytokines

Debridement

dental implants

enzyme-linked immunosorbent assay

interleukin-17

peri-implantitis

Abstract

Background. One of the ever-increasing complications related to dental implants, with controversy over how to control it, is peri-implant disease. The aim of this study was to evaluate the adjunctive use of enamel matrix derivative (EMD) to mechanical debridement (MD) in patients with these conditions in terms of clinical parameters and cytokine levels of peri-implant crevicular fluid (PICF). Methods. In the present double-blind clinical trial, 46 patients with peri-implant diseases (pocket depth (PD) ≥ 4mm and bone loss≤ 2mm) were randomly divided into control and test groups. Two different therapeutic protocols, consisting of non-surgical MD with and without the application of EMD were considered for the two groups. Clinical parameters and sampling from PICF were carried out before treatment and 3-month postoperative interval. ELISA was used for the analysis of PICF samples in relation to IL-6 and IL-17 cytokines levels. Results. After 3 months, no specific changes were observed in the control group in terms of bleeding on probing (BOP) and PD; however, in the test group, use of EMD resulted in a significant decrease in BOP (from 75%to25%) and PD (from 4. 5 to 3mm) (P Conclusions. The results showed that non-surgical MD alone cannot be effective in the treatment of severe peri-implant mucositis and initial peri-implantitis, and use of EMD can be considered an adjunct to MD in the non-surgical treatment of these lesions, although no complete recovery was achieved after 3 months.

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APA: Copy

POURABBAS, REZA, KASHEFIMEHR, ATABAK, & Moradi, Aouzar. (2019). Anti-inflammatory properties of enamel matrix derivative on non-surgical management of periimplant mucosal inflammation. JOURNAL OF ADVANCED PERIODONTOLOGY AND IMPLANT DENTISTRY, 11(suppl A (19th international congress of Iranian Academy of Periodontology)), 0-0. SID. https://sid.ir/paper/775366/en

Vancouver: Copy

POURABBAS REZA, KASHEFIMEHR ATABAK, Moradi Aouzar. Anti-inflammatory properties of enamel matrix derivative on non-surgical management of periimplant mucosal inflammation. JOURNAL OF ADVANCED PERIODONTOLOGY AND IMPLANT DENTISTRY[Internet]. 2019;11(suppl A (19th international congress of Iranian Academy of Periodontology)):0-0. Available from: https://sid.ir/paper/775366/en

IEEE: Copy

REZA POURABBAS, ATABAK KASHEFIMEHR, and Aouzar Moradi, “Anti-inflammatory properties of enamel matrix derivative on non-surgical management of periimplant mucosal inflammation,” JOURNAL OF ADVANCED PERIODONTOLOGY AND IMPLANT DENTISTRY, vol. 11, no. suppl A (19th international congress of Iranian Academy of Periodontology), pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/775366/en

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