GROWTH FACTOR AND LAMININ EFFECT WITH MUSCULAR FIBER SHEATH ON REPAIRING OF THE SCIATICA NERVE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

TORABI S.; MAHMOUDI R.; ROZBEHI A.; JAFARI BARMAK M.; RAD P.; DELAVIZ H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Armaghane Danesh Year:2014 | Volume:18 | Issue:10 (82) Page(s): 847-858

Download Full-Text

Persian Verion

View:

757

Download:

Cites:

Information Journal Paper

Title

GROWTH FACTOR AND LAMININ EFFECT WITH MUSCULAR FIBER SHEATH ON REPAIRING OF THE SCIATICA NERVE

Author(s)

Keywords

SCIATIC FUNCTIONAL INDEXQ2

MUSCLE GRAFTQ2

NGFQ2

LAMININQ3

Abstract

Background & aim: Peripheral nerve injuries which can lead to a physical disability. If the defect is very low, direct suture without tension on both ends of the cut nerve regeneration is considered as a standard procedure. Otherwise, to reconstruct the axons, the gap must be filled by graft material in order to the guidance. Due to the similarity of the matrix tubular skeletal muscle and nerve muscles graft was used to repair in this study.Methods: In the present experimental study, 42 female Wistar rats were divided into three groups and underwent surgery. In the first group a narrow strip of muscle was prepared by freezing – thawing, and later sutured between the distal and proximal sciatic nerve. In the second group, the gap caused by MUSCLE GRAFT was regenerated and the nerve growth factor and LAMININ was injected into the graft. In the control group, the two ends of the cut nerve were hidden beneath the adjacent muscles. Next, a group of rats with SCIATIC FUNCTIONAL INDEX was investigated for the behavioral. On the other group were examined for histological studies after two months.Results: SCIATIC FUNCTIONAL INDEX and Mean counts of myelinated fibers in two graft groups compared with the control group was significant (p<0.05). Statistical analysis was performed using ANOVA test.Conclusion: co-axially aligned MUSCLE GRAFTs were an appropriate alternative substitute for repairing. It seems that the nerve growth factor and LAMININ have a positive role in axonal regeneration and functional recovery acceleration.

Cites

No record.

References

No record.

Cite

APA: Copy

TORABI, S., MAHMOUDI, R., ROZBEHI, A., JAFARI BARMAK, M., RAD, P., & DELAVIZ, H.. (2014). GROWTH FACTOR AND LAMININ EFFECT WITH MUSCULAR FIBER SHEATH ON REPAIRING OF THE SCIATICA NERVE. ARMAGHAN DANESH, 18(10 (82)), 847-858. SID. https://sid.ir/paper/78142/en

Vancouver: Copy

TORABI S., MAHMOUDI R., ROZBEHI A., JAFARI BARMAK M., RAD P., DELAVIZ H.. GROWTH FACTOR AND LAMININ EFFECT WITH MUSCULAR FIBER SHEATH ON REPAIRING OF THE SCIATICA NERVE. ARMAGHAN DANESH[Internet]. 2014;18(10 (82)):847-858. Available from: https://sid.ir/paper/78142/en

IEEE: Copy

S. TORABI, R. MAHMOUDI, A. ROZBEHI, M. JAFARI BARMAK, P. RAD, and H. DELAVIZ, “GROWTH FACTOR AND LAMININ EFFECT WITH MUSCULAR FIBER SHEATH ON REPAIRING OF THE SCIATICA NERVE,” ARMAGHAN DANESH, vol. 18, no. 10 (82), pp. 847–858, 2014, [Online]. Available: https://sid.ir/paper/78142/en

Related Journal Papers