EFFECT OF L-CARNITINE ON PLATELET BACTERIAL CONTAMINATION AND PLATELET METABOLISM DURING 5 DAYS OF STORAGE OF PLATELET CONCENTRATES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

VELASHJERDI Z.; DEYHIM M.R.; RAZJOU F.; EYDI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: The Scientific Journal of Iranian Blood Transfusion Year:2018 | Volume:15 | Issue:1 Page(s): 1-11

Download Full-Text

Persian Verion

View:

921

Download:

Cites:

Information Journal Paper

Title

EFFECT OF L-CARNITINE ON PLATELET BACTERIAL CONTAMINATION AND PLATELET METABOLISM DURING 5 DAYS OF STORAGE OF PLATELET CONCENTRATES

Author(s)

VELASHJERDI Z. | DEYHIM M.R. | RAZJOU F. | EYDI A. | Issue Writer Certificate

Keywords

L-CARNITINEQ1

BLOOD PLATELETSQ2

METABOLISMQ1

Abstract

Background and Objectives: Platelet concentrate is one of the important blood products. The platelets are stored at that is an optimum temperature for bacterial growth, so the platelet bacterial contamination is considered to be the most common infective risk factor in blood transfusion.Materials and Methods: In this experimental study, we selected ten platelet concentrates from healthy donors prepared by Iranian Blood Transfusion Inovation Center and stored at 22oC with gentle agitation up to 5 days. Then, the antibacterial effects of LC on the platelet concentrates inoculated with the gram-positive Staphylococcus epidermidis as well as the effects of LC on the metabolic parameters of the platelets were measured.Results: The results showed that L-CARNITINE in concentration of 50 mM could significantly decrease the growth of 1.5×106CFU/ml Staphylococcus epidermidis (p < 0.01). Moreover, the concentration of 50 mM could better maintain the LDH enzyme activity in the platelet concentrate during storage (P day3 = 0.003, P day5 = 0.002). Lactate concentration in LC treated platelet was lower than the control group at day 5 of storage (P day5 = 0.008) and also pH of the platelet was better maintained in LC treated platelets. In addition, the platelet count showed less decrease in LC treated platelets compared with control group at day 5 of storage (P day5 = 0.007).Conclusions: L-CARNITINE can improve the METABOLISM and quality of the platelet concentrates, as an additive, during the storage and it can decrease bacterial growth in the platelet concentrates during the storage.

Cites

No record.

References

No record.

Cite

APA: Copy

VELASHJERDI, Z., DEYHIM, M.R., RAZJOU, F., & EYDI, A.. (2018). EFFECT OF L-CARNITINE ON PLATELET BACTERIAL CONTAMINATION AND PLATELET METABOLISM DURING 5 DAYS OF STORAGE OF PLATELET CONCENTRATES. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 15(1 ), 1-11. SID. https://sid.ir/paper/78334/en

Vancouver: Copy

VELASHJERDI Z., DEYHIM M.R., RAZJOU F., EYDI A.. EFFECT OF L-CARNITINE ON PLATELET BACTERIAL CONTAMINATION AND PLATELET METABOLISM DURING 5 DAYS OF STORAGE OF PLATELET CONCENTRATES. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2018;15(1 ):1-11. Available from: https://sid.ir/paper/78334/en

IEEE: Copy

Z. VELASHJERDI, M.R. DEYHIM, F. RAZJOU, and A. EYDI, “EFFECT OF L-CARNITINE ON PLATELET BACTERIAL CONTAMINATION AND PLATELET METABOLISM DURING 5 DAYS OF STORAGE OF PLATELET CONCENTRATES,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 15, no. 1 , pp. 1–11, 2018, [Online]. Available: https://sid.ir/paper/78334/en

Related Journal Papers