SURVEY OF HBV AND HCV MARKERS IN HAEMODIALYSIS AND THALASSEMIA, SOUTH KHORASAN, BIRJAND 2007

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AZARKAR Z.; SHARIFZADEH GH.R.; CHAHKANDI T.; MAHMOUDIRAD A.; SANDOUGHI MASOUMEH; REZAEI NARJES

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Journal: The Scientific Journal of Iranian Blood Transfusion Year:2009 | Volume:6 | Issue:3 (24) Page(s): 233-237

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Title

SURVEY OF HBV AND HCV MARKERS IN HAEMODIALYSIS AND THALASSEMIA, SOUTH KHORASAN, BIRJAND 2007

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Keywords

HEPATITIS B VIRUSQ3

HEPATITIS C VIRUSQ3

THALASSEMIAQ3

DIALYSISQ3

Abstract

Background and Objectives: HBV and HCV are the most common types of viral hepatitis in THALASSEMIA and hemdialysis patients. The most important risk factor in these two groups of patients is blood transfusion. This descriptive study was aimed to determine the prevalence rate of hepatitis B and C among DIALYSIS and thalassemic patients.Materials and Methods: This prospective cross-sectional study was performed on all thalassemic patients in South Khorasan and dialyzed patients in Birjand city. A questionnaire aimed to retrieve information about age, sex, frequency of annual blood transfusion, time of diagnosis, and history of vaccination was prepared. Their sera were tested for HBs Ag, anti-HBc, anti-HBs, and anti- HCV Ab by using Elisa third generation. SPSS software was finally used for data analysis.Results: Out of 38 thalassemic patients, 21 (54.1%) were male and 17 (45.9%) female. All of them had been vaccinated for HBV. Out of thalassemics, 56.8% were anti-HBs positive (CI 95%=40.8- 72.8). We also studied 30 dialyzed patient’s 66.7% of whom male. Out of the 30 dialyzed patients, 36.7% had been vaccinated for HBV with 26.7% being anti-HBs positive, 6.7% HBs Ag positive (CI 95%=3.4-30) and 16.7% anti-HBc positive and statistical analysis showed no significant correlation between HBs Ag positivity and anti-HBs positivity (p=0.36).onclusions: Our results showed that prevalence of HCV in thalassemic and DIALYSIS patients was zero, while prevalence of HBV in multitransfused patients in this study was 3%. It is a reemphasis on the role of effective blood donor selection and screening in decreasing prevalence and incidence of infection.

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APA: Copy

AZARKAR, Z., SHARIFZADEH, GH.R., CHAHKANDI, T., MAHMOUDIRAD, A., SANDOUGHI, MASOUMEH, & REZAEI, NARJES. (2009). SURVEY OF HBV AND HCV MARKERS IN HAEMODIALYSIS AND THALASSEMIA, SOUTH KHORASAN, BIRJAND 2007. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 6(3 (24)), 233-237. SID. https://sid.ir/paper/78441/en

Vancouver: Copy

AZARKAR Z., SHARIFZADEH GH.R., CHAHKANDI T., MAHMOUDIRAD A., SANDOUGHI MASOUMEH, REZAEI NARJES. SURVEY OF HBV AND HCV MARKERS IN HAEMODIALYSIS AND THALASSEMIA, SOUTH KHORASAN, BIRJAND 2007. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2009;6(3 (24)):233-237. Available from: https://sid.ir/paper/78441/en

IEEE: Copy

Z. AZARKAR, GH.R. SHARIFZADEH, T. CHAHKANDI, A. MAHMOUDIRAD, MASOUMEH SANDOUGHI, and NARJES REZAEI, “SURVEY OF HBV AND HCV MARKERS IN HAEMODIALYSIS AND THALASSEMIA, SOUTH KHORASAN, BIRJAND 2007,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 6, no. 3 (24), pp. 233–237, 2009, [Online]. Available: https://sid.ir/paper/78441/en

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