SEROEPIDEMIOLOGIC EVALUATION OF RH SYSTEM MAJOR ANTIGENS (D, C, E, C, E) AND THEIR PHENOTYPES AMONG THE BLOOD DONORS IN KHORRAMABAD, IRAN

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ABDI JAHANGIR; KIANI ALI ASGHAR

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Journal: The Scientific Journal of Iranian Blood Transfusion Year:2009 | Volume:6 | Issue:3 (24) Page(s): 219-226

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Title

SEROEPIDEMIOLOGIC EVALUATION OF RH SYSTEM MAJOR ANTIGENS (D, C, E, C, E) AND THEIR PHENOTYPES AMONG THE BLOOD DONORS IN KHORRAMABAD, IRAN

Author(s)

ABDI JAHANGIR | KIANI ALI ASGHAR | Issue Writer Certificate

Keywords

PHENOTYPEQ3

RHESUS BLOOD-GROUP SYSTEMQ3

BLOOD DONORSQ2

IRANQ3

Abstract

Background and Objectives: Knowing the frequency of D, C, E ,c ,e antigens is necessary for population studies and plays a significant role in paternity tests. The purpose of this research is to determine the frequency of Rh antigens and their PHENOTYPEs in Khorramabad BLOOD DONORS and to set up the data bank of individuals lacking the very common antigens.Materials and Methods: The study was carried out as census on 1236 BLOOD DONORS referring to Khorramabad Blood Center. Appropriate cell suspensions were incubated with several Rh antiserums; then, based on the type of reactions observed and most probable genotypes identified by reference to tables of Rh antigens frequency in black and white populations, PHENOTYPEs for main antigens were determined.Results: Out of all observed reactions, the most common ones were associated with the e antigen (94.34%, CI 95%=91.57-97.10) and the least with the E antigen (43.5%). As to D antigens, 92.88% (CI 95%=90.14-95.65) of individuals were positive and 7.4% were negative. The results were 73.5% and 71.2% for C and c antigens, respectively.Conclusions: A 92.88% frequency for D antigen in Khorramabad city BLOOD DONORS indicates a high regional difference in frequency. As a result, Rh negative blood units in the region deserve much more attention. In the meantime, the relatively significant frequency of e negative donors in the region more than ever emphasizes the necessity of setting up an e negative blood bank.

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APA: Copy

ABDI, JAHANGIR, & KIANI, ALI ASGHAR. (2009). SEROEPIDEMIOLOGIC EVALUATION OF RH SYSTEM MAJOR ANTIGENS (D, C, E, C, E) AND THEIR PHENOTYPES AMONG THE BLOOD DONORS IN KHORRAMABAD, IRAN. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 6(3 (24)), 219-226. SID. https://sid.ir/paper/78442/en

Vancouver: Copy

ABDI JAHANGIR, KIANI ALI ASGHAR. SEROEPIDEMIOLOGIC EVALUATION OF RH SYSTEM MAJOR ANTIGENS (D, C, E, C, E) AND THEIR PHENOTYPES AMONG THE BLOOD DONORS IN KHORRAMABAD, IRAN. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2009;6(3 (24)):219-226. Available from: https://sid.ir/paper/78442/en

IEEE: Copy

JAHANGIR ABDI, and ALI ASGHAR KIANI, “SEROEPIDEMIOLOGIC EVALUATION OF RH SYSTEM MAJOR ANTIGENS (D, C, E, C, E) AND THEIR PHENOTYPES AMONG THE BLOOD DONORS IN KHORRAMABAD, IRAN,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 6, no. 3 (24), pp. 219–226, 2009, [Online]. Available: https://sid.ir/paper/78442/en

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