RT-PCR TEDT IN CONFIRMED DIAGNOSIS OF HCV IN HCV-AB POSITIVE CASES

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TAJBAKHSH ELAHEH; MOMTAZ H.; DOUSTI ABAS; YAGHOUBI RAMIN; MOUMENI MANOUCHEHR

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Title

RT-PCR TEDT IN CONFIRMED DIAGNOSIS OF HCV IN HCV-AB POSITIVE CASES

Author(s)

Keywords

RT PCRQ4

HEPATITIS C VIRUSQ3

IRANQ3

Abstract

Background and Objectives: Despite the fact that blood transfusion is a life saving procedure, there still exists a minimum risk for the occurrence of transfusion transmitted infections including HCV with adverse reactions and heavy cost being the immediate outcome. HCV is a health problem all over the world with 200 million people affected. IRAN is classified as the country with low prevalence rate for HCV; however, the new HCV incidence rate is in an increasing trend.Materials and Methods: In this cross sectional research, 50 Elisa and RIBA positive samples detected out of 11472 blood donors were evaluated by RT-PCR method. The positive cases had never received any treatment for hepatitis by the time the test results were reported.Results: The results of RIBA and RT-PCR tests were compared. In RIBA, 60% of cases were positive, 16% indeterminate, and 24% negative. While in RT-PCR, the positive cases were 62% and the negative ones 38%.Conclusions: The results of the present study show that the use of serological tests in diagnostic HCV infection, the application of RT-PCR in confirmation of positive results, and employment of RIBA tests in confirmation of indeterminate cases are all effective in detection of HCV infection.

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APA: Copy

TAJBAKHSH, ELAHEH, MOMTAZ, H., DOUSTI, ABAS, YAGHOUBI, RAMIN, & MOUMENI, MANOUCHEHR. (2009). RT-PCR TEDT IN CONFIRMED DIAGNOSIS OF HCV IN HCV-AB POSITIVE CASES. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 5(4 (21)), 287-292. SID. https://sid.ir/paper/78571/en

Vancouver: Copy

TAJBAKHSH ELAHEH, MOMTAZ H., DOUSTI ABAS, YAGHOUBI RAMIN, MOUMENI MANOUCHEHR. RT-PCR TEDT IN CONFIRMED DIAGNOSIS OF HCV IN HCV-AB POSITIVE CASES. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2009;5(4 (21)):287-292. Available from: https://sid.ir/paper/78571/en

IEEE: Copy

ELAHEH TAJBAKHSH, H. MOMTAZ, ABAS DOUSTI, RAMIN YAGHOUBI, and MANOUCHEHR MOUMENI, “RT-PCR TEDT IN CONFIRMED DIAGNOSIS OF HCV IN HCV-AB POSITIVE CASES,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 5, no. 4 (21), pp. 287–292, 2009, [Online]. Available: https://sid.ir/paper/78571/en

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