FREQUENCY OF WEAK D ALLELES IN BLOOD DONORS BY MOLECULAR METHODS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DANESHVAR Z.; AMIRIZADEH N.; OODI A.; GOUDARZI S.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON) Year:2018 | Volume:15 | Issue:2 Page(s): 95-104

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

819

Download:

Cites:

Information Journal Paper

Title

FREQUENCY OF WEAK D ALLELES IN BLOOD DONORS BY MOLECULAR METHODS

Author(s)

DANESHVAR Z. | AMIRIZADEH N. | OODI A. | GOUDARZI S. | Issue Writer Certificate

Keywords

BLOOD DONORSQ2

GENOTYPEQ2

ALLELESQ1

Abstract

Background and Objectives: Detection of weak D blood type can lead to the saving of RhD negative blood components and can reduce RhIG consumption. Therefore, determining the frequency of weak D ALLELES in our country is necessary.Materials and Methods: In this descriptive study, a total of 105 blood samples with weak expression of D antigen from 21 provinces among Iranian BLOOD DONORS were studied. The phenotype of samples was tested for Rh D, C, c, E and e antigens by routine serological methods. Weak D variants were evaluated by PCR-SSP, RFLP and DNA sequencing methods.Results: Among 105 weak D samples, 9 weak D ALLELES and 2 partial D ALLELES were found. The most prevalent weak D type in our population was weak D type 15 (38.1%), weak D Type 1 (10.48%), Type 5 (7.62%), Type 4 (4.76%), Type 80 (3.8%), Type 3 (1.9%) and Type 11, Type 8 , Type 100 each (0.95%) and Partial D DLO (8.57%), and partial D V a /DAU (0.95%). We also observed the correlation between weak D type 15 and E antigen and weak D type 1 and Partial D DLO and C antigen.Conclusions: There is a significant difference between the prevalence of Weak D variants among our BLOOD DONORS compared to European and American white populations with a high incidence of weak D 1, 2 and 3, equally compared to African population with a high incidence of Partial D and weak D type 4, as well as Asian population with a high prevalence of Del.

Cites

No record.

References

Transfusion strategy for weak D Type 4. 0 based on RHD alleles and RH haplotypes in Tunisia

Cite

APA: Copy

DANESHVAR, Z., AMIRIZADEH, N., OODI, A., & GOUDARZI, S.. (2018). FREQUENCY OF WEAK D ALLELES IN BLOOD DONORS BY MOLECULAR METHODS. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 15(2 ), 95-104. SID. https://sid.ir/paper/78760/en

Vancouver: Copy

DANESHVAR Z., AMIRIZADEH N., OODI A., GOUDARZI S.. FREQUENCY OF WEAK D ALLELES IN BLOOD DONORS BY MOLECULAR METHODS. THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2018;15(2 ):95-104. Available from: https://sid.ir/paper/78760/en

IEEE: Copy

Z. DANESHVAR, N. AMIRIZADEH, A. OODI, and S. GOUDARZI, “FREQUENCY OF WEAK D ALLELES IN BLOOD DONORS BY MOLECULAR METHODS,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 15, no. 2 , pp. 95–104, 2018, [Online]. Available: https://sid.ir/paper/78760/en

Related Journal Papers