EFFECT OF HEXANIC AND HYDRO ALCOHOLIC EXTRACT OF CANNABIS SATIVA FLOWERS ON INFLAMMATORY PAW EDEMA IN RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FARHADI MOGHADAM B.; FEREIDONI M.; ASADOLLAHI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Gorgan University of Medical Sciences Year:2016 | Volume:17 | Issue:4 (56) Page(s): 30-35

Download Full-Text

Persian Verion

View:

879

Download:

Cites:

Information Journal Paper

Title

EFFECT OF HEXANIC AND HYDRO ALCOHOLIC EXTRACT OF CANNABIS SATIVA FLOWERS ON INFLAMMATORY PAW EDEMA IN RATS

Author(s)

FARHADI MOGHADAM B. | FEREIDONI M. | ASADOLLAHI A. | Issue Writer Certificate

Keywords

CANNABIS SATIVAQ2

EDEMAQ3

LOWER LIMBQ2

RATQ2

Abstract

Background and Objective: Cyclooxygenase 1 and 2 activities on arachidonic fatty acids of cell membrane produces prostaglandins which involved in inflammatory processes. This study was done to evaluate the effect of hexanic and hydro alcoholic extract of CANNABIS SATIVA flowers on inflammatory paw EDEMA in RATs.Methods: In this experimental study, 56 male Wistar RATs were allocated into the control, sham, sodium salicylate (300mg/kg/bw) and hydro alcoholic extract of heated flowers in 1, 10 and 50 mg/kg/bw, hydro alcoholic extract of unheated flowers in 50mg/kg/bw and hexanic extract of heated flower in 50mg/kg/bw, intraperitonally. 30 minutes after injection, inflammatory EDEMA volume due to sub plantar injection of formalin (0.05 ml, 2.5%) measeared using plethysmometric method.Results: Intraperitonally injection of 50mg/kg/bw, of hydro alcoholic and hexanic extracts of heated flowers significantly reduced in inflammatory paw EDEMA induced by formalin (P<0.05). Also, 50mg/kg/bw, hydro alcoholic extract of unheated flowers reduced the inflammatory paw EDEMA in comparison with heated extracts (P<0.05).Conclusion: Hydro alcoholic extract of heated flowers decreased inflammation-induced paw EDEMA in dose-dependent manner. The extract of unheated flowers, leads to more reduction of the inflammatory paw EDEMA in comparison to heated flower extract, it can be due to carboxylated cannabinoid present in the hydro alcoholic extract of unheated flowers.

Cites

EFFECT OF INTRAPERITONEAL ADMINISTRATION OF HYDROALCOHOLIC AND HEXANIC EXTRACT OF HEATED FEMALE CANNABIS SATIVA FLOWERTOPS ON ANXIETY BEHAVIOR, MOTOR COORDINATION AND LOCOMOTOR ACTIVITY IN THE MALE RATS

References

Cite

APA: Copy

FARHADI MOGHADAM, B., FEREIDONI, M., & ASADOLLAHI, A.. (2016). EFFECT OF HEXANIC AND HYDRO ALCOHOLIC EXTRACT OF CANNABIS SATIVA FLOWERS ON INFLAMMATORY PAW EDEMA IN RATS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 17(4 (56)), 30-35. SID. https://sid.ir/paper/79209/en

Vancouver: Copy

FARHADI MOGHADAM B., FEREIDONI M., ASADOLLAHI A.. EFFECT OF HEXANIC AND HYDRO ALCOHOLIC EXTRACT OF CANNABIS SATIVA FLOWERS ON INFLAMMATORY PAW EDEMA IN RATS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;17(4 (56)):30-35. Available from: https://sid.ir/paper/79209/en

IEEE: Copy

B. FARHADI MOGHADAM, M. FEREIDONI, and A. ASADOLLAHI, “EFFECT OF HEXANIC AND HYDRO ALCOHOLIC EXTRACT OF CANNABIS SATIVA FLOWERS ON INFLAMMATORY PAW EDEMA IN RATS,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 4 (56), pp. 30–35, 2016, [Online]. Available: https://sid.ir/paper/79209/en

Related Journal Papers