FOLLOWING IN VITRO SPERMATOGENESIS WITH LONG-TERM PRESERVED SPERMATOGONIAL STEM CELLS

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MOHAQIQ MAHDI; MOVAHEDIN MANSOUREH; MAZAHERI ZOHREH; AMIR JANATI NASER

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Journal: PATHOBIOLOGY RESEARCH Year:2016 | Volume:19 | Issue:3 Page(s): 1-15

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Title

FOLLOWING IN VITRO SPERMATOGENESIS WITH LONG-TERM PRESERVED SPERMATOGONIAL STEM CELLS

Author(s)

MOHAQIQ MAHDI | MOVAHEDIN MANSOUREH | MAZAHERI ZOHREH | AMIR JANATI NASER | Issue Writer Certificate

Keywords

SPERMATOGENESISQ2

SPERMATOGONIAL STEM CELLSQ2

IN VITROQ1

LONG-TERM PRESERVATIONQ1

Abstract

Spermatogonial stem cells are foundation of the male reproductive system. These cells are the only conduit capable of transferring genetic traits from one generation to the next. Isolation and long-term preservation of spermatogonial stem cells for use in inducing spermatogenesis is one technique to preserve fertility in male patients who need chemotherapy. In vitro spermatogenesis is an alternative to achieve this goal. The use of an optimal model of human spermatogenesis is a major step in understanding the physiology and genetic pathways in the male reproductive system. In vitro spermatogenesis is crucial to reducing a complex process into smaller parts for experimentation, manipulation, and deriving cellular and molecular level knowledge. Is it possible to manipulate the paracrine environment and separately evaluate the effects of growth factors. Different in vitro culture systems are used to explore alternatives to spermatogenesis and obtain mature, functional spermatozoa for ultimate use in infertility treatment. In order to present a useful and practical method, this study provides an overview of different methods for the long-term preservation of spermatogonial stem cells and in vitro culture systems used in spermatogenesis.

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APA: Copy

MOHAQIQ, MAHDI, MOVAHEDIN, MANSOUREH, MAZAHERI, ZOHREH, & AMIR JANATI, NASER. (2016). FOLLOWING IN VITRO SPERMATOGENESIS WITH LONG-TERM PRESERVED SPERMATOGONIAL STEM CELLS. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), 19(3), 1-15. SID. https://sid.ir/paper/81221/en

Vancouver: Copy

MOHAQIQ MAHDI, MOVAHEDIN MANSOUREH, MAZAHERI ZOHREH, AMIR JANATI NASER. FOLLOWING IN VITRO SPERMATOGENESIS WITH LONG-TERM PRESERVED SPERMATOGONIAL STEM CELLS. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES)[Internet]. 2016;19(3):1-15. Available from: https://sid.ir/paper/81221/en

IEEE: Copy

MAHDI MOHAQIQ, MANSOUREH MOVAHEDIN, ZOHREH MAZAHERI, and NASER AMIR JANATI, “FOLLOWING IN VITRO SPERMATOGENESIS WITH LONG-TERM PRESERVED SPERMATOGONIAL STEM CELLS,” PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), vol. 19, no. 3, pp. 1–15, 2016, [Online]. Available: https://sid.ir/paper/81221/en

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