EFFECTS OF EIGHT WEEKS TESTOSTERONE ENANTHATE ADMINISTRATION AND RESISTANCE TRAINING ON LIVER ENZYME PROFILE IN MALE RATS

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DEHBASHI MOHSEN; RASHIDLAMIR AMIR; MOUSAVI ZAHRA; ATARZADEH HOSEINI SEYED REZA; ZAEIMI MAHDIEH

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Journal: Journal of Sabzevar University of Medical Sciences Year:2018 | Volume:25 | Issue:2 Page(s): 55-62

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Title

EFFECTS OF EIGHT WEEKS TESTOSTERONE ENANTHATE ADMINISTRATION AND RESISTANCE TRAINING ON LIVER ENZYME PROFILE IN MALE RATS

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Keywords

LIVERQ1

RATQ1

STEROIDQ2

TESTOSTERONE ENANTHATEQ2

Abstract

Introduction: The utilization of STEROID derivatives has become a major concern in the sport community. The aim of the present study was the investigation of eight weeks TESTOSTERONE ENANTHATE (TE) administrationand resistance training (RT) effects on LIVER enzyme profile in male RATs.Materials and Methods: The thirty five RATs (age: 10 weeks, weight: 12±200 g) randomly was divided to five groups (n=7) including: (1) control+placebo, (2) RT+placebo, (3) TE, (4) RT+moderate dose of TE, and (5) RT+high dose of TE. The resistance training was consisted of climbing (5 reps/3 sets) a ladder carrying a load suspended from the tail for 8 weeks. At the end, whole blood samples were obtained from the orbital sinus and serum activity of LIVER enzymes including AST, GGT, ALT and ALP was measured by spectrophotometry.Findings: AST activity RT+HTE group was significantly higher than C, RT and TE groups. This enzyme also had marked higher activity in RT+MTE group compared with C and RT groups (p<0.05).Conclusion: Considering to the significant elevation of AST activity in RT+TE (high and moderate doses) groups and insignificant increase in activity of this enzyme in TE group, it can therefore be concluded resistance training and TESTOSTERONE ENANTHATE have synergistic effect. No change was observed in ALT activity; hence AST increasing may have other origins except LIVER

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APA: Copy

DEHBASHI, MOHSEN, RASHIDLAMIR, AMIR, MOUSAVI, ZAHRA, ATARZADEH HOSEINI, SEYED REZA, & ZAEIMI, MAHDIEH. (2018). EFFECTS OF EIGHT WEEKS TESTOSTERONE ENANTHATE ADMINISTRATION AND RESISTANCE TRAINING ON LIVER ENZYME PROFILE IN MALE RATS. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 25(2 ), 55-62. SID. https://sid.ir/paper/81793/en

Vancouver: Copy

DEHBASHI MOHSEN, RASHIDLAMIR AMIR, MOUSAVI ZAHRA, ATARZADEH HOSEINI SEYED REZA, ZAEIMI MAHDIEH. EFFECTS OF EIGHT WEEKS TESTOSTERONE ENANTHATE ADMINISTRATION AND RESISTANCE TRAINING ON LIVER ENZYME PROFILE IN MALE RATS. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;25(2 ):55-62. Available from: https://sid.ir/paper/81793/en

IEEE: Copy

MOHSEN DEHBASHI, AMIR RASHIDLAMIR, ZAHRA MOUSAVI, SEYED REZA ATARZADEH HOSEINI, and MAHDIEH ZAEIMI, “EFFECTS OF EIGHT WEEKS TESTOSTERONE ENANTHATE ADMINISTRATION AND RESISTANCE TRAINING ON LIVER ENZYME PROFILE IN MALE RATS,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 25, no. 2 , pp. 55–62, 2018, [Online]. Available: https://sid.ir/paper/81793/en

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