The Effects of Anabolic Steroids Boldenone with Eight Weeks Aerobic Exercise on Histopathological Changes in Cerebellum Male Wistar Rats

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Yahyaei Behrooz; Nouri Mahnaz; RAMEZANI MAEDEH

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Journal: Journal of Sabzevar University of Medical Sciences Year:2019 | Volume:25 | Issue:6 Page(s): 885-894

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Information Journal Paper

Title

The Effects of Anabolic Steroids Boldenone with Eight Weeks Aerobic Exercise on Histopathological Changes in Cerebellum Male Wistar Rats

Author(s)

Yahyaei Behrooz | Nouri Mahnaz | RAMEZANI MAEDEH | Issue Writer Certificate

Keywords

aerobic exerciseQ1

BoldenoneQ1

cerebellumQ2

histopathologyQ2

Abstract

Introduction: Today, the anabolic steroids widely used but side effects aren’ t wellknown. This research aimed to study the effects of anabolic steroids Bulednon with aerobic training on cerebellar tissue changes of male Wistar rat during 2016. Materials & Methods: This study was conducted on mice Wistar rat. 49 rats were divided into seven groups: control (n=7), sham (n=7), no practice at a dose of 2 mg/kg Boldenone (n=7), without practicing at a dose of 5mg/kg Boldenone (n=7), group exercise (n=7), a workout at a dose of 2 mg/kg dose Boldenone (n=7) and practice 5 mg/kg Boldenone (n=7). The mice were kept under identical conditions and with the same power and endurance activities according to their protocol and drug Boldenone, the intervention groups were injected. After eight weeks, the mice were anesthetized and sacrificed. The tissue samples from the cerebellum were prepared. Results: There was a significant difference between the groups treated with exercise and control group without exercise. In the group exercise amount and rate of change, the cerebellum tissue is significantly lower than the control group. And even there was a significant difference between the two groups with different dosages also under endurance exercise. Conclusion: The results showed that endurance and aerobic activity for eight weeks can be largely Boldenone effects of the drug on mice reduces brain tissue but with increasing doses Boldenone creation these changes are inevitable.

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APA: Copy

Yahyaei, Behrooz, Nouri, Mahnaz, & RAMEZANI, MAEDEH. (2019). The Effects of Anabolic Steroids Boldenone with Eight Weeks Aerobic Exercise on Histopathological Changes in Cerebellum Male Wistar Rats. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 25(6 ), 885-894. SID. https://sid.ir/paper/81880/en

Vancouver: Copy

Yahyaei Behrooz, Nouri Mahnaz, RAMEZANI MAEDEH. The Effects of Anabolic Steroids Boldenone with Eight Weeks Aerobic Exercise on Histopathological Changes in Cerebellum Male Wistar Rats. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;25(6 ):885-894. Available from: https://sid.ir/paper/81880/en

IEEE: Copy

Behrooz Yahyaei, Mahnaz Nouri, and MAEDEH RAMEZANI, “The Effects of Anabolic Steroids Boldenone with Eight Weeks Aerobic Exercise on Histopathological Changes in Cerebellum Male Wistar Rats,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 25, no. 6 , pp. 885–894, 2019, [Online]. Available: https://sid.ir/paper/81880/en

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