Calculation of the effective dose in the internal organs from 99mTc-Somatostatine analogue using MCNPX simulation code

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Mahmoudi Mirhashemi Mohsen; SHIRMARDI SEYED PEZHMAN; NEGARESTANI ALI; ERFANI MOSTAFA

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Journal: Journal of Sabzevar University of Medical Sciences Year:2019 | Volume:26 | Issue:1 Page(s): 81-87

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Title

Calculation of the effective dose in the internal organs from 99mTc-Somatostatine analogue using MCNPX simulation code

Author(s)

Mahmoudi Mirhashemi Mohsen | SHIRMARDI SEYED PEZHMAN | NEGARESTANI ALI | ERFANI MOSTAFA | Issue Writer Certificate

Keywords

MCNPX simulation codeQ1

MIRD phantomQ2

radiopharmaceuticalQ1

99mTc-OctreotideQ1

Abstract

Background & Objectives radiopharmaceuticals have several applications in medicine such as diagnostic and therapeutic. radiopharmaceuticals with gamma emitter radionuclides are used more in diagnostics. It is due to the low absorption of gamma in the tissue relative to the particles of beta and alpha. The aim of this research is calculation of effective dose distribution in human body due to injection of 99mTc-Octrotide (Somatostatine analogue) in mice body. Materials & Methods Effective dose in human body is estimated using MIRD phantom and MCNPX for different organs. Energy of source and tally are considered 140keV and F6, respectively. Fubdubgs Effective dose after injection of 99mTc-Octreotide is estimated by MCNPX simulation code. The adrenals and pancreas received the most effective dose relative to the other organs 6mSv/185MBq, 1. 5 mSv/185MBq, respectively. Discussion & Conclusion The results showed that the adrenal and pancreas are the organs of at risk in 99mTc-Octreotide radiopharmaceutical imaging.

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References

ESTIMATION OF ORGAN ABSORBED DOSES IN PATIENTS FROM (99M) TC-DIPHOSPHONATE USING THE DATA OF MIRDOSE SOFTWARE

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APA: Copy

Mahmoudi Mirhashemi, Mohsen, SHIRMARDI, SEYED PEZHMAN, NEGARESTANI, ALI, & ERFANI, MOSTAFA. (2019). Calculation of the effective dose in the internal organs from 99mTc-Somatostatine analogue using MCNPX simulation code. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 26(1 ), 81-87. SID. https://sid.ir/paper/82151/en

Vancouver: Copy

Mahmoudi Mirhashemi Mohsen, SHIRMARDI SEYED PEZHMAN, NEGARESTANI ALI, ERFANI MOSTAFA. Calculation of the effective dose in the internal organs from 99mTc-Somatostatine analogue using MCNPX simulation code. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;26(1 ):81-87. Available from: https://sid.ir/paper/82151/en

IEEE: Copy

Mohsen Mahmoudi Mirhashemi, SEYED PEZHMAN SHIRMARDI, ALI NEGARESTANI, and MOSTAFA ERFANI, “Calculation of the effective dose in the internal organs from 99mTc-Somatostatine analogue using MCNPX simulation code,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 1 , pp. 81–87, 2019, [Online]. Available: https://sid.ir/paper/82151/en

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