EFFECT OF POMEGRANATE SEED EXTRACT (PGSE) ON OXIDATIVE STRESS DUO TO ISCHEMIA/HYPOPERFUSION IN MALE RAT HIPPOCAMPUS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHASEMZADEHDEHKORDI K.; RAFIEIRAD M.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES Year:2015 | Volume:23 | Issue:5 Page(s): 9-16

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

733

Download:

Cites:

Information Journal Paper

Title

EFFECT OF POMEGRANATE SEED EXTRACT (PGSE) ON OXIDATIVE STRESS DUO TO ISCHEMIA/HYPOPERFUSION IN MALE RAT HIPPOCAMPUS

Author(s)

GHASEMZADEHDEHKORDI K. | RAFIEIRAD M. | Issue Writer Certificate

Keywords

BRAIN ISCHEMIAQ2

OXIDATIVE STRESSQ1

POMEGRANATE SEED EXTRACTQ2

MALONDIALDEHYDEQ1

THIOLQ2

Abstract

Introduction: Free radicals are involved in the development and exacerbation of neurological diseases and antioxidants play a protective role. In this study the effect of oral administration of POMEGRANATE SEED EXTRACT (PGSE) was investigated on assess the rate of lipid peroxidation and measuring the rate of THIOL groups (-SH) in an animal model of chronic ischemic hypoperfusion.Material & methods: The rats were randomly divided into three groups: control group, ischemia group and ischemia group receiving the POMEGRANATE SEED EXTRACT. For ischemia in the rat, general carotid arteries blocked by means of skin suture with two tight knot around the vessel (top and bottom) and then arteries were completely intersect. Then the rats' brains were extracted to assess the rate of lipid peroxidation and measuring the rate of THIOL groups (-SH).Findings: Our results showed that MALONDIALDEHYDE and THIOL in ischemia group has significantly increased (p< 0.001) than in control group and rate of MALONDIALDEHYDE and THIOL in ischemia group receiving the extract of pomegranate seed has significantly decreased, respectively (p<0.001) and (p<0.001), than in ischemia group.Discussion & Conclusion: POMEGRANATE SEED EXTRACT possibly with powerful antioxidant properties, can improve the effect of ischemia such as production of free radicals.

Cites

No record.

References

No record.

Cite

APA: Copy

GHASEMZADEHDEHKORDI, K., & RAFIEIRAD, M.. (2015). EFFECT OF POMEGRANATE SEED EXTRACT (PGSE) ON OXIDATIVE STRESS DUO TO ISCHEMIA/HYPOPERFUSION IN MALE RAT HIPPOCAMPUS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 23(5), 9-16. SID. https://sid.ir/paper/90048/en

Vancouver: Copy

GHASEMZADEHDEHKORDI K., RAFIEIRAD M.. EFFECT OF POMEGRANATE SEED EXTRACT (PGSE) ON OXIDATIVE STRESS DUO TO ISCHEMIA/HYPOPERFUSION IN MALE RAT HIPPOCAMPUS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2015;23(5):9-16. Available from: https://sid.ir/paper/90048/en

IEEE: Copy

K. GHASEMZADEHDEHKORDI, and M. RAFIEIRAD, “EFFECT OF POMEGRANATE SEED EXTRACT (PGSE) ON OXIDATIVE STRESS DUO TO ISCHEMIA/HYPOPERFUSION IN MALE RAT HIPPOCAMPUS,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 23, no. 5, pp. 9–16, 2015, [Online]. Available: https://sid.ir/paper/90048/en

Related Journal Papers