EFFECT OF YELLOW PLANT ALOEVERA AND ALCOHOLIC EXTRACT OF PROPOLISON IMPROVING DIABETIC RAT ULCERS

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JAFARI M.; SHIRAVI A.; NOROUZI P.; KHAKSARI M.

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Journal: Journal of Ilam University of Medical Sciences Year:2016 | Volume:24 | Issue:1 Page(s): 174-185

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Information Journal Paper

Title

EFFECT OF YELLOW PLANT ALOEVERA AND ALCOHOLIC EXTRACT OF PROPOLISON IMPROVING DIABETIC RAT ULCERS

Author(s)

JAFARI M. | SHIRAVI A. | NOROUZI P. | KHAKSARI M. | Issue Writer Certificate

Keywords

DIABETESQ1

ALOEVERAQ1

RATSQ2

PROPOLISQ2

Abstract

Introduction: Ulcer and its complications can cause many problems for patients.Therefore, understanding the factors that can influence wound healing and prevent the spread of damage is important. Thestudy aimed to identify factors affecting wound healing yellow ALOEVERA plant and PROPOLIS extracts.Materials & methods: In this study, 50 malewistar RATS (180-130 Grm) were randomly selected and divided into five groups: control, diabetic RATS, diabetic RATS treated with ALOEVERA plant, diabetic RATS treated with PROPOLIS extract and diabetic RATStreated with their combination. Then eachof five groups after being injured 2 cm inlength, were made on the skin and the wound healing process was followed daily.Wound area was measured at the next daysand MATLAB software was used forcalculating the percentage of wound healing. In order to study pathology on days 4, 7, 14 and 21 of the wounds were sampledand one way analysis of variance(ANOVA) test was used to compare the differences between the groups and Tukey post hoc test was used to specify where the difference occurred.Findings: The mean healing time in the experimental group treated with acombination of ALOEVERA plant and PROPOLISextract was less than the other groups(P≤0.01). Also, the histological study Confirmed improvement in skin text uretreatment with ALOEVERA plant and PROPOLISextract significant difference compared tothe other groups (P≤0.01).Diacussion & Conclusions: The study showed that topical administration of ALOEVERA plant and PROPOLIS extract accelerate healing of diabetic ulcers.

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APA: Copy

JAFARI, M., SHIRAVI, A., NOROUZI, P., & KHAKSARI, M.. (2016). EFFECT OF YELLOW PLANT ALOEVERA AND ALCOHOLIC EXTRACT OF PROPOLISON IMPROVING DIABETIC RAT ULCERS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 24(1), 174-185. SID. https://sid.ir/paper/90132/en

Vancouver: Copy

JAFARI M., SHIRAVI A., NOROUZI P., KHAKSARI M.. EFFECT OF YELLOW PLANT ALOEVERA AND ALCOHOLIC EXTRACT OF PROPOLISON IMPROVING DIABETIC RAT ULCERS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;24(1):174-185. Available from: https://sid.ir/paper/90132/en

IEEE: Copy

M. JAFARI, A. SHIRAVI, P. NOROUZI, and M. KHAKSARI, “EFFECT OF YELLOW PLANT ALOEVERA AND ALCOHOLIC EXTRACT OF PROPOLISON IMPROVING DIABETIC RAT ULCERS,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 1, pp. 174–185, 2016, [Online]. Available: https://sid.ir/paper/90132/en

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