SURVIVAL RATES AND PROGNOSTIC FACTORS IN COLORECTAL CANCER PATIENTS

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MOGHIMI DEHKORDI B.; SAFAEI AZADEH; ZALI MOHAMMAD REZA

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Paper Information

Journal: Journal of Ilam University of Medical Sciences Year:2008 | Volume:16 | Issue:1 Page(s): 33-43

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Title

SURVIVAL RATES AND PROGNOSTIC FACTORS IN COLORECTAL CANCER PATIENTS

Author(s)

MOGHIMI DEHKORDI B. | SAFAEI AZADEH | ZALI MOHAMMAD REZA | Issue Writer Certificate

Keywords

COLORECTAL CANCERQ3

PROGNOSISQ2

KAPLAN-MEIERQ3

COX PROPORTIONAL HAZARD MODELQ3

Abstract

Introduction: The incidence of COLORECTAL CANCER has increased in Iran in recent years and become the fourth most common cancer in both sexes. The aim of this study was to define the prognostic factors in Iranian COLORECTAL CANCER patients using univariate and multivariate methods.Materials & methods: All patients with colorectal carcinoma admitted to the Cancer Registry Center of Shahid Beheshti university of medical sciences; during Jan 1, 2002 to Jan 1, 2007 were analyzed. Survival rates of all the cases were determined. The probability curves for survival were calculated according to the Kaplan–Meier Method, then compared by the Log-rank test. Multivariate analysis was carried out using the COX PROPORTIONAL HAZARD MODEL.Findings: Out of 1138 cases, a survival information was obtained on 1127 patients, 690 males (61.2%) and 437 females (38.8%). The mean survival time was 105.1(CI: 95,1-115.1) months. The KAPLAN-MEIER method indicated that, the 1, 3, 5, 7, 10 and 15 years survival rates were 91.1, 73.1, 61.0, 54.9, 47.9, 25 and 9 percent, respectively. These variables were independent prognostic factors for survival as determined by multivariate analysis, that is, tumor size, metastasis of tumor, body mass index, marital status, and grade of tumor.Conclusion: Our results showed that stage of tumor, state of metastasis, grade of tumor and tumor size should be considered the most important prognostic factors in COLORECTAL CANCER patients. There fore, early detection of cancer using screening programs can improve survival in such patients.

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References

SURVIVAL ANALYSIS OF COLORECTAL CANCERS YAZD 1981-2000

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APA: Copy

MOGHIMI DEHKORDI, B., SAFAEI, AZADEH, & ZALI, MOHAMMAD REZA. (2008). SURVIVAL RATES AND PROGNOSTIC FACTORS IN COLORECTAL CANCER PATIENTS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 16(1), 33-43. SID. https://sid.ir/paper/90512/en

Vancouver: Copy

MOGHIMI DEHKORDI B., SAFAEI AZADEH, ZALI MOHAMMAD REZA. SURVIVAL RATES AND PROGNOSTIC FACTORS IN COLORECTAL CANCER PATIENTS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;16(1):33-43. Available from: https://sid.ir/paper/90512/en

IEEE: Copy

B. MOGHIMI DEHKORDI, AZADEH SAFAEI, and MOHAMMAD REZA ZALI, “SURVIVAL RATES AND PROGNOSTIC FACTORS IN COLORECTAL CANCER PATIENTS,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 1, pp. 33–43, 2008, [Online]. Available: https://sid.ir/paper/90512/en

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