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Information Journal Paper

Title

The acute effect of aerobic exercise on hypothalamic nesfatin-1 gene expression in diabetic male rats with STZ

Pages

  104-113

Abstract

 Background and Aim: Nesfetin-1 is known as the Neuropeptide which interferes with appetite and glucose hemostasis. It has been reported its amount in healthful persons than diabetes sick is variable and changes according to the exercise. The aim of the present study is to investigate the effects of acute aerobic exercise on Nesfatin-1 gene expression in diabetic rats. Materials and Methods: In this experimental study, has utilized the diabetic Wistar rat'sstagy rats with STZ (12 week-age, 220-240 gr-weight). Animals were divided into 4 groups: Continuous exercise (COE-0) and control (CO), (Immediately after exercise were killed) and continuous (COE-2) and control (C-2), (Two hours after the exercise, they were killed), respectively. Group COE performed exercise at a speed of 18 meters per minute, equivalent to 65% of maximum speed, for 40 minutes on the treadmill. Hypothalamus tissue was excised for determination of Nesfatin-1 gene expression by RT-PCR methods. Data were analyzed using SPSS software (version 20) with independent T-test (P <0. 01). Results: The current results indicated that the levels of Nesfatin-1 gene expression, increased significantly in training group immediately and two hours after exercise when compared with Control group yourself. Conclusion: It seems a session of Continuous exercise may increase the hypothalamic expression of male Wistar rats with diabetes Nesfatin-1 immediately and two hours after the exercise.

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    Cite

    APA: Copy

    MORADI, MOHAMMAD, Shabkhiz, Fatemah, Khalafi, Moosa, & Talebi, Vahid. (2018). The acute effect of aerobic exercise on hypothalamic nesfatin-1 gene expression in diabetic male rats with STZ. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 25(2 ), 104-113. SID. https://sid.ir/paper/95782/en

    Vancouver: Copy

    MORADI MOHAMMAD, Shabkhiz Fatemah, Khalafi Moosa, Talebi Vahid. The acute effect of aerobic exercise on hypothalamic nesfatin-1 gene expression in diabetic male rats with STZ. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;25(2 ):104-113. Available from: https://sid.ir/paper/95782/en

    IEEE: Copy

    MOHAMMAD MORADI, Fatemah Shabkhiz, Moosa Khalafi, and Vahid Talebi, “The acute effect of aerobic exercise on hypothalamic nesfatin-1 gene expression in diabetic male rats with STZ,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 25, no. 2 , pp. 104–113, 2018, [Online]. Available: https://sid.ir/paper/95782/en

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