REVIEW ON THE LABORATORY DIAGNOSIS OF CRIMEAN-CONGO HEMORRHAGIC FEVER

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MAJIDZADEH ARDABILI K.; SOLEIMANI M.; GHEILANCHI LANGRODI A.

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Paper Information

Journal: Annals of Military and Health Sciences Research Year:2012 | Volume:9 | Issue:4 (SERIAL NUMBER 36) Page(s): 275-284

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Title

REVIEW ON THE LABORATORY DIAGNOSIS OF CRIMEAN-CONGO HEMORRHAGIC FEVER

Author(s)

MAJIDZADEH ARDABILI K. | SOLEIMANI M. | GHEILANCHI LANGRODI A. | Issue Writer Certificate

Keywords

CRIMEAN-CONGO HEMORRHAGIC FEVER (CCHF)Q2

LABORATORY TESTSQ2

DIAGNOSISQ2

Abstract

Background: Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal zeonosis disease caused by a tick-borne virus from the Bunyaviridae family. The CCHF virus is transmitted to humans through the bite of the Ixodid ticks or contact with the blood or tissues of CCHF patients or infected livestock. Human infections begin with the nonspecific febrile symptoms, but progress to a serious hemorrhagic syndrome with a case fatality rate of 2-50%. As Rapid and precise DIAGNOSIS approach is critical for control, treatment and detection of patients and is useful for epidemiological studies.Materials and Methods: We conducted a review study on the different research works on DIAGNOSIS field in the world and Iran scientific databases, according to laboratory DIAGNOSIS of CCHFin bio safety, sampling and DIAGNOSIS assays aspects.Results: Laboratory DIAGNOSIS of CCHF is based on three approaches: Virus Isolation, Serological assays (IIF, RPHA, and ELISA) and antigen detect assays (ELISA, RT-PCR, Real Time RT-PCR and Microarray) Conclusion: Early DIAGNOSIS is critical for patient therapy, prevention of potential nosocomial infections and in biological attacks. Also, the ability to distinguish between an infection with a reassortant and a nonreassortant variant may have prognostic value. According to Iranian health center facilities, we should design and established domestic methods in each three approaches especially in BSL4 facilities in Iran.

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APA: Copy

MAJIDZADEH ARDABILI, K., SOLEIMANI, M., & GHEILANCHI LANGRODI, A.. (2012). REVIEW ON THE LABORATORY DIAGNOSIS OF CRIMEAN-CONGO HEMORRHAGIC FEVER. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, 9(4 (SERIAL NUMBER 36)), 275-284. SID. https://sid.ir/paper/96521/en

Vancouver: Copy

MAJIDZADEH ARDABILI K., SOLEIMANI M., GHEILANCHI LANGRODI A.. REVIEW ON THE LABORATORY DIAGNOSIS OF CRIMEAN-CONGO HEMORRHAGIC FEVER. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH[Internet]. 2012;9(4 (SERIAL NUMBER 36)):275-284. Available from: https://sid.ir/paper/96521/en

IEEE: Copy

K. MAJIDZADEH ARDABILI, M. SOLEIMANI, and A. GHEILANCHI LANGRODI, “REVIEW ON THE LABORATORY DIAGNOSIS OF CRIMEAN-CONGO HEMORRHAGIC FEVER,” ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, vol. 9, no. 4 (SERIAL NUMBER 36), pp. 275–284, 2012, [Online]. Available: https://sid.ir/paper/96521/en

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