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Information Journal Paper

Title

Evaluation of Aflatoxin M1 Contamination in Pasteurized Milk in Kerman and Rafsanjan Cities in 2019: A Descriptive Study

Pages

  1163-1178

Abstract

 Background and Objectives: Aflatoxins are known as causative factors of hepatic and extra-hepatic carcinogenesis within humans. Aflatoxin B1 enters the animal body through contaminated feed and is partially secreted in Milk after being metabolized in the liver to Aflatoxin M1 (AFM1). The aim of this study was to determine the amount of Aflatoxin M1 to evaluate the quality status of pasteurized Milk. Materials and Methods: This descriptive study was performed to determine the occurrence of AFM1 in 39 pasteurized Milk samples collected during winter and summer 2019 in Kerman and Rafsanjan cities. Aflatoxin analysis was carried out by high-performance liquid chromatography. The non-parametric Mann– Whitney U and Kruskal– Wallis H tests were used to analyze data. Results: Aflatoxin M1 was detected in 100% of the pasteurized Milk ranging from 5. 41 to 125. 37 ng/l. Toxin levels in 2. 6% (1 sample) and 17. 9% (7 samples) of the pasteurized Milk samples exceeded the Iranian national standard (100 ng/L) and EU (50 ng/L) limit, respectively. The mean concentration of aflatoxin in pasteurized Milk samples produced in various regions was significantly different (p <0. 05). The Carcinogenic Risk assessment of AFM1 in Milk was estimated, indicating that adult consumers in Kerman and Rafsanjan city are not at considerable cancer risk (HI<1). However, it was not the case for children (1

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    APA: Copy

    DINI, A., REZAEIAN, M., ESMAEILI, A., Sotoodeh, L., & ASGARIAN, A.. (2021). Evaluation of Aflatoxin M1 Contamination in Pasteurized Milk in Kerman and Rafsanjan Cities in 2019: A Descriptive Study. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 19(11 ), 1163-1178. SID. https://sid.ir/paper/965401/en

    Vancouver: Copy

    DINI A., REZAEIAN M., ESMAEILI A., Sotoodeh L., ASGARIAN A.. Evaluation of Aflatoxin M1 Contamination in Pasteurized Milk in Kerman and Rafsanjan Cities in 2019: A Descriptive Study. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES[Internet]. 2021;19(11 ):1163-1178. Available from: https://sid.ir/paper/965401/en

    IEEE: Copy

    A. DINI, M. REZAEIAN, A. ESMAEILI, L. Sotoodeh, and A. ASGARIAN, “Evaluation of Aflatoxin M1 Contamination in Pasteurized Milk in Kerman and Rafsanjan Cities in 2019: A Descriptive Study,” JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, vol. 19, no. 11 , pp. 1163–1178, 2021, [Online]. Available: https://sid.ir/paper/965401/en

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