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Information Journal Paper

Title

Comparing the Eff ect of Classical and Modifi ed Thoracolumbar Interfascial Plane Block on Postoperative Pain and IL-6 Level in Posterior Lumbar Decompression and Stabilization Surgery

Author(s)

 ROSITA TANTRI AIDA | Besthadi Sukmono Raden | Apul Lumban Tobing Singkat Dohar | Natali Christella | Issue Writer Certificate 

Pages

  0-0

Abstract

 Background: Ultrasound (US)-guided classical and modifi ed thoracolumbar interfascial plane (TLIP) blocks are often used to provide adequate analgesia after lumbar spinal surgery. Postoperative pro-infl ammatory interleukin 6 (IL-6) blood concentrations after lumbar spine surgery are related to postoperative pain and infl ammation. Objectives: The purpose of this prospective randomized parallel controlled study was to assess postoperative pain and serum levels of pro-infl ammatory IL-6 after posterior lumbar decompression and stabilization surgery with a classical and modifi ed technique of TLIP block. Methods: This prospective randomized, single-blinded controlled pilot study was conducted on eight patients who will undergo posterior lumbar decompression and stabilization surgery. After obtaining the ethical approval and an informed consent, all subjects were randomly allocated into the classic TLIP group and the modifi ed TLIP group. Following general anesthesia induction, 20 mL bupivacaine 0. 25% was injected on each side in interfascialis plane between m. longissimus and m. iliocostalis in modifi ed TLIP group and between m. multifi dus and m. longissimus in classical TLIP group. Intraoperative hemodynamic (blood pressure and heart rate) and noxious stimulation response level (qNOX), postoperative IL-6 level, 24-hour morphine consumption, and numerical rating score were recorded and analyzed. Results: The median of IL-6 level was found to be lower in the modifi ed TLIP group 12 hours postoperatively compared to classic TLIP (29. 91 (8. 56 – 87. 61) vs. 46. 87 (2. 87 – 92. 35)). The mean Numerical Rating Scale (NRS) in the modifi ed TLIP block was comparable with the classic TLIP group, although it was lower than the classic TLIP group (2. 75  1. 5 vs. 3. 75  1. 7 at 6 hours and 3. 5  1. 3 vs. 4  1. 6 12 hours postoperatively). However, there was no diff erence in intraoperative hemodynamic, Qnox value, and total postoperative morphine consumption between the two groups. Conclusions: Our study showed that modifi ed TLIP block resulted in lower IL-6 level and NRS 12 hours postoperatively compared to classical TLIP block. However, there were no diff erences in total postoperative morphine consumption between the two groups.

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    APA: Copy

    ROSITA TANTRI, AIDA, Besthadi Sukmono, Raden, Apul Lumban Tobing, Singkat Dohar, & Natali, Christella. (2022). Comparing the Eff ect of Classical and Modifi ed Thoracolumbar Interfascial Plane Block on Postoperative Pain and IL-6 Level in Posterior Lumbar Decompression and Stabilization Surgery. ANESTHESIOLOGY AND PAIN MEDICINE, 12(2), 0-0. SID. https://sid.ir/paper/984784/en

    Vancouver: Copy

    ROSITA TANTRI AIDA, Besthadi Sukmono Raden, Apul Lumban Tobing Singkat Dohar, Natali Christella. Comparing the Eff ect of Classical and Modifi ed Thoracolumbar Interfascial Plane Block on Postoperative Pain and IL-6 Level in Posterior Lumbar Decompression and Stabilization Surgery. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2022;12(2):0-0. Available from: https://sid.ir/paper/984784/en

    IEEE: Copy

    AIDA ROSITA TANTRI, Raden Besthadi Sukmono, Singkat Dohar Apul Lumban Tobing, and Christella Natali, “Comparing the Eff ect of Classical and Modifi ed Thoracolumbar Interfascial Plane Block on Postoperative Pain and IL-6 Level in Posterior Lumbar Decompression and Stabilization Surgery,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 12, no. 2, pp. 0–0, 2022, [Online]. Available: https://sid.ir/paper/984784/en

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