THE EFFECT OF HYDROALCOHOLIC EXTRACT OF SALVIA OFFICINALIS L. ON THE INFLAMMATORY REDUCTION IN MALE MICE

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KHAKPOUR SHAHRZAD; KHOSRAVI MARYAM; JAFARI MARANDI SAYEH; AHADI ALI MITRA

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Journal: MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY Year:2014 | Volume:24 | Issue:3 Page(s): 136-142

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Title

THE EFFECT OF HYDROALCOHOLIC EXTRACT OF SALVIA OFFICINALIS L. ON THE INFLAMMATORY REDUCTION IN MALE MICE

Author(s)

KHAKPOUR SHAHRZAD | KHOSRAVI MARYAM | JAFARI MARANDI SAYEH | AHADI ALI MITRA | Issue Writer Certificate

Keywords

SALVIA OFFICINALIS L.Q2

ANTI-INFLAMMATORY EFFECTQ3

DEXAMETHASONEQ2

MICEQ2

Abstract

Background: Resistance of microorganisms to chemical drugs makes the medicinal plants to be considered in folk medicine. Antidepressants, antimicrobials, antinociceptives and antioxidants effects of SALVIA OFFICINALIS L. have been evaluated. In this study, the anti-inflammatory like effect of SALVIA OFFICINALIS L. hydroalcoholic extract was studied on the inflammation induced byxylene in the right ear of male MICE.Materials and methods: In the experimental groups, 0.03ml of xylene was injected subcutaneously in the right ear of MICE weighing 20-25 g. 30 minutes before xylene injection, SALVIA OFFICINALIS L. extracts in doses of 10, 50, 100, 150 mg / kg and DEXAMETHASONE 15mg/ kg were administered intraperitoneally. The inflammation was measured according to the weight difference of a plug with 6mm of thickness in treated and non- treated ears of MICE. After treatments, white blood cells of animal’s serum were counted.Results: The results showed that SALVIA OFFICINALIS L. hydroalcoholic extract reduces inflammation comparable with DEXAMETHASONE effect.Conclusion: The hydroalcoholic extract of SALVIA OFFICINALIS L. has ANTI-INFLAMMATORY EFFECT and this effect may be due to flavonoid and terpene components in plant.

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APA: Copy

KHAKPOUR, SHAHRZAD, KHOSRAVI, MARYAM, JAFARI MARANDI, SAYEH, & AHADI ALI, MITRA. (2014). THE EFFECT OF HYDROALCOHOLIC EXTRACT OF SALVIA OFFICINALIS L. ON THE INFLAMMATORY REDUCTION IN MALE MICE. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, 24(3), 136-142. SID. https://sid.ir/paper/98822/en

Vancouver: Copy

KHAKPOUR SHAHRZAD, KHOSRAVI MARYAM, JAFARI MARANDI SAYEH, AHADI ALI MITRA. THE EFFECT OF HYDROALCOHOLIC EXTRACT OF SALVIA OFFICINALIS L. ON THE INFLAMMATORY REDUCTION IN MALE MICE. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY[Internet]. 2014;24(3):136-142. Available from: https://sid.ir/paper/98822/en

IEEE: Copy

SHAHRZAD KHAKPOUR, MARYAM KHOSRAVI, SAYEH JAFARI MARANDI, and MITRA AHADI ALI, “THE EFFECT OF HYDROALCOHOLIC EXTRACT OF SALVIA OFFICINALIS L. ON THE INFLAMMATORY REDUCTION IN MALE MICE,” MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, vol. 24, no. 3, pp. 136–142, 2014, [Online]. Available: https://sid.ir/paper/98822/en

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