EXPERIMENTAL STUDY OF CELL DEATH IN LYMPHOID TISSUES OF SPF CHICKENS WITH AVIAN INFLUENZA VIRUS (H9N2) INFECTION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DOUSTAR Y.; TOROUGHI R.; HASHEMI MEHRDAD; MOHAJERI D.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY Year:2009 | Volume:19 | Issue:2 (56) Page(s): 81-86

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

616

Download:

Cites:

Information Journal Paper

Title

EXPERIMENTAL STUDY OF CELL DEATH IN LYMPHOID TISSUES OF SPF CHICKENS WITH AVIAN INFLUENZA VIRUS (H9N2) INFECTION

Author(s)

DOUSTAR Y. | TOROUGHI R. | HASHEMI MEHRDAD | MOHAJERI D. | Issue Writer Certificate

Keywords

AVIAN INFLUENZA VIRUSQ3

LYMPHOID TISSUEQ3

CELL DEATHQ3

Abstract

Background: Influenza virus causes the CELL DEATH in animals and human beings. CELL DEATH occurs in two manners as necrosis and apoptosis. In this study, the types of CELL DEATH in LYMPHOID TISSUEs assessed in experimentally infected chickens with H9N2 AVIAN INFLUENZA VIRUS (A/chicken/Iran/772/2000).Materials and methods: In this experimental study, 20 SPF chickens aged 3 weeks were divided equally into two groups. The treatment group was infected with 0.2 ml of 1:10 dilution and 107.5EID50 titer of the virus intra-nasally and the control group was treated with saline normal in the same volume. Lymphoid organs including spleen, thymus and bursa of fabricius were collected after 72 hours of treatment and tissue specimens were fixed in 10% buffered formalin. Microscopic sections with the thickness of 5-6 micron were stained by H&E method.Results: Histopathological examination of LYMPHOID TISSUEs of the experimental groups indicated necrosis, apoptosis and lymphoid depletionsin the treatment group. Apoptotic changes in the splenic tissues were significantly different between two groups (p<0.001). There were no significant differences between two groups in terms of changes in the thymus and bursa of fabricius. However, Necrotic changes and lymphoid depletions in the splenic tissues, thymus and bursa of fabricius were significantly different between two groups (p <0.001).Conclusion: This study indicates that H9N2 AVIAN INFLUENZA VIRUS is able to cause LYMPHOID TISSUE damages through induction of apoptosis and necrosis.

Cites

No record.

References

No record.

Cite

APA: Copy

DOUSTAR, Y., TOROUGHI, R., HASHEMI, MEHRDAD, & MOHAJERI, D.. (2009). EXPERIMENTAL STUDY OF CELL DEATH IN LYMPHOID TISSUES OF SPF CHICKENS WITH AVIAN INFLUENZA VIRUS (H9N2) INFECTION. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, 19(2 (56)), 81-86. SID. https://sid.ir/paper/98854/en

Vancouver: Copy

DOUSTAR Y., TOROUGHI R., HASHEMI MEHRDAD, MOHAJERI D.. EXPERIMENTAL STUDY OF CELL DEATH IN LYMPHOID TISSUES OF SPF CHICKENS WITH AVIAN INFLUENZA VIRUS (H9N2) INFECTION. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY[Internet]. 2009;19(2 (56)):81-86. Available from: https://sid.ir/paper/98854/en

IEEE: Copy

Y. DOUSTAR, R. TOROUGHI, MEHRDAD HASHEMI, and D. MOHAJERI, “EXPERIMENTAL STUDY OF CELL DEATH IN LYMPHOID TISSUES OF SPF CHICKENS WITH AVIAN INFLUENZA VIRUS (H9N2) INFECTION,” MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, vol. 19, no. 2 (56), pp. 81–86, 2009, [Online]. Available: https://sid.ir/paper/98854/en

Related Journal Papers