High frequency of SCCmec type IV and multidrug-resistant SCCmec type I among hospital acquired methicillin-resistant Staphylococcus aureus isolates in Birjand Imam Reza Hospital, Iran

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Sadeghi Moghaddam Toktam; NAMAEI MOHAMMAD HASAN; AFSHAR DAVOUD; YOUSEFI MASOUD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MICROBIOLOGY Year:2022 | Volume:14 | Issue:1 Page(s): 67-75

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

High frequency of SCCmec type IV and multidrug-resistant SCCmec type I among hospital acquired methicillin-resistant Staphylococcus aureus isolates in Birjand Imam Reza Hospital, Iran

Author(s)

Sadeghi Moghaddam Toktam | NAMAEI MOHAMMAD HASAN | AFSHAR DAVOUD | YOUSEFI MASOUD | Issue Writer Certificate

Keywords

Methicillin-resistant Staphylococcus aureus

Drug resistance

Multidrug-resistant

mecA gene

Molecular typ-ing

Polymerase chain reaction

Abstract

Background and Objectives: The ever-increasing of antibiotic resistance in methicillin-resistant Staphylococcus aureus (MRSA) has become a major threat to public health worldwide. Molecular typing is used to determine the source of MRSA infections as well as to control and prevent the spread of these pathogens. The present study aimed to investigate the char-acteristics of staphylococcal cassette chromosome mec (SCCmec) types and antibiotic resistance of community-acquired (CA-) and hospital acquired (HA-) MRSA isolates. Materials and Methods: In this cross-sectional study, the antibiotic susceptibility patterns of 109 clinical S. aureus isolates were determined by the Kirby-Bauer disk-diffusion and microdilution broth methods. MRSA isolates were confirmed using the polymerase chain reaction (PCR) method for the detection of the mecA gene. SCCmec typing was performed by a mul-tiplex PCR assay among MRSA isolates. Results: The prevalence of MRSA isolates was 39. 4%. Linezolid, vancomycin, and ceftaroline were the most effective agents against MRSA isolates. The incidence of multidrug-resistant (MDR) and resistance to most antibiotics were signifi-cantly higher in MRSA than methicillin-susceptible S. aureus (MSSA) isolates (P<0. 05). SCCmec types I, III, and IV were identified in 27. 9%, 23. 3%, and 37. 2% of MRSA isolates, respectively. SCCmec type I and IV were the most prevalent SCCmec types in HA-MRSA isolates (each was 32. 4%). While SCCmec type IV (66. 7%) was the most frequently SCCmec type associated with CA-MRSA isolates. Conclusion: Our findings demonstrated a high rate of MDR among MRSA isolates. The high existence of SCCmec type IV was reported among the HA-MRSA isolates, which can indicate the spread of MRSA community isolates to hospital settings. Therefore, appropriate antibiotic stewardship plans and microbiological surveillance initiatives must be implemented in healthcare facilities to monitor and limit the spread of these resistant bugs.

Multimedia

No record.

Cites

References

No record.

Cite

APA: Copy

Sadeghi Moghaddam, Toktam, NAMAEI, MOHAMMAD HASAN, AFSHAR, DAVOUD, & YOUSEFI, MASOUD. (2022). High frequency of SCCmec type IV and multidrug-resistant SCCmec type I among hospital acquired methicillin-resistant Staphylococcus aureus isolates in Birjand Imam Reza Hospital, Iran. IRANIAN JOURNAL OF MICROBIOLOGY, 14(1), 67-75. SID. https://sid.ir/paper/988855/en

Vancouver: Copy

Sadeghi Moghaddam Toktam, NAMAEI MOHAMMAD HASAN, AFSHAR DAVOUD, YOUSEFI MASOUD. High frequency of SCCmec type IV and multidrug-resistant SCCmec type I among hospital acquired methicillin-resistant Staphylococcus aureus isolates in Birjand Imam Reza Hospital, Iran. IRANIAN JOURNAL OF MICROBIOLOGY[Internet]. 2022;14(1):67-75. Available from: https://sid.ir/paper/988855/en

IEEE: Copy

Toktam Sadeghi Moghaddam, MOHAMMAD HASAN NAMAEI, DAVOUD AFSHAR, and MASOUD YOUSEFI, “High frequency of SCCmec type IV and multidrug-resistant SCCmec type I among hospital acquired methicillin-resistant Staphylococcus aureus isolates in Birjand Imam Reza Hospital, Iran,” IRANIAN JOURNAL OF MICROBIOLOGY, vol. 14, no. 1, pp. 67–75, 2022, [Online]. Available: https://sid.ir/paper/988855/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops