Background and Objective: Resistance exercises are recognized as an important part of women's fitness and fitness programs. But the effect of resistance training with different intensities on damages and muscle growth in girls is not fully clear. Therefore, the aim of this study was to investigate the effect of 6 weeks of resistance training with two different intensities on selected metabolic parameters among active young girls.Subjects and Methods: Thirty six active student girls (mean age 20.7 ± 1.3 years, weight 58.4 ± 1.3 kg, height 164.1 ± 0.9 cm, and BMI of 23.1 ± 0.5 kg/m2) were divided into three groups: resistance training high intensity (70-90% of one repetition maximum, for 6 weeks; n=12), resistance training low intensity (40-60% of one repetition maximum, for 6 weeks; n=12) and no training control group (n=12). Blood samples were taken before and 24 hours after the end of the protocol to measure the levels of creatine kinase, growth hormone, testosterone, cortisol and insulin-like growth factor.Results: One-way ANOVA results showed a significant difference in growth hormone (P<0.006), testosterone (P<0.05) and cortisol (P<0.03), and non-significant differences in keratin kinase (P<0.17) and growth factor Insulin (P<0.27) between the 3 groups. The result of post hoc test showed a significant increase in growth hormone levels in resistance training groups with high and low intensity compared to control group (P<0.007 and P<0.03), testosterone levels in resistance training group with low intensity compared to control (P<0.05), and cortisol levels in resistance training group compared to control group (P<0.02).Conclusion: The results of this study showed that there is no difference between high and low intensity resistance training on the levels of muscular metabolic indices in active girls.