Medical Journal of Tabriz University of Medical Sciences
Year:2018 | Volume:40 | Issue:3 |Papers Count:15

Background: The gluteal-to-Tensor Fascia Latae muscle activation index is considered a valuable finding in therehabilitation of disease such as low back pain. The aim of this study was to compare the effect of lumbo-pelvicgeneral and selected exercises on pain, movement control and gluteal and TFL muscles activation in patients withlumbar movement control impairment. Methods: 39 subjects with nonspecific chronic low back pain and lumbar movement control impairment wererecruited. Before and after the implementation of two different types of general and selected training protocols forlumbo-pelvic area, the pain, movement control and muscle activity measurement were done by using visualanalogue scale, Lumajoki tests and surface electromyography respectively. Results: Mean Age of study was with mean age of 33. 4± 6. 13 years old. The results showed that both groups oftraining increases the activity of the gluteal muscles but only the selected training led to pain decreases andmovement control improvement. Selected training group consists of side step, clam with elastic resistance aroundthighs (CLAM), unilateral bridge (uni BRG), hip extension in quadruped on elbows with knee extending (QKE) andhip extension in quadruped on elbows with knee flexed (QKF) exercises increases more in the gluteal-to-Tensorindex index that this is due to increased Gluteal muscles activity and decreased Tensor Fascia Latae activity afterperforming these exercises that this is a very important clinical finding. Conclusion: It is recommended that if the goal of rehabilitation is to preferentially activation and strengtheningthe gluteal muscles while minimizing Tensor Fascia Latae activation, then the CLAM, SIDE STEP, UniBRG, QKE, and QKF exercises appear to be most appropriate.

Background: During the history, researchers studied the healing effects of traditional medicine against many infectious diseases. In order to explore therapeutic role of Propolis Ethanolic Extract (EEP), an experimental cutaneous candidiasis was induced in goat model as InVivo study. Methods: Four young healthy goats without any skin fungal infection were selected from different herds. The skin on both sides of the lateral thoracic and flank areas of the studied animals were shaved. The Candida albicans PCTP 5027 suspension were inoculated on each site. On day 8th, 64 large abscesses and pimples were appeared on all inoculated sites. All treatments begun on 8th day. Wideness of Cutaneous Candidiasis lesions on all sites of all goats scaled by a ruler during this study in centimeter and monitored planimetrically and analyzed statistically. Biopsy were collected on particular days under local anesthesia after intradermal inoculation date. Sections were stained with hematoxylin and eosin (H & E) and special stain of G. M. S. for fungal infection. Results: Comparison of the values for different treatments revealed a significant reduction in abscess size and inflammatory signs in EEP treated group comparing to Nystatin treated, Glycerin treated and untreated groups (P≤ 0/05). Histological findings showed anti-inflammatory results, with better cutaneous repair, sebaceous, sweat gland, and hair follicle regeneration in EEP group, better than other treatment groups (P≤ 0. 05). Conclusion: EEP has a considerable anti-inflammatory and antifungal effects even more better than Nystatin, without its side effects (scar formation, shedding of infected crust, "treatment dependent hypersensitivity").

Background: The aim of this research was to investigate the effect of twelve-week aerobic exercise with moderate intensity on IL-6 level and depression in 50-65 years old women with syndrome metabolic and its relationship with indexes of syndrome metabolic. Methods: 24 women with metabolic syndrome (MetS) voluntarily took part in the present study. Participants were randomly divided in two groups of MetS exercise (ME), MetS control (MC), each comprised of 12. During the first week ME group participated in three sets of eight-minute aerobic exercise training (AT) program and they have 5 minute rest part between the sets. One minute was added to the duration of exercise sets weekly basis. Beck depression questionnaire and blood samples were conducted before and after twelve-week. Results: IL-6 level and depression significantly decreased (P˂ 0. 05) as effects of three-month aerobic exercise. Z syndrome metabolic score underwent a significant increase (P˂ 0. 05). A significant relationship (P˂ 0. 05) was also noticed among improvement of metabolic syndrome, IL-6 level and depression decrease. Conclusion: The twelve-week aerobic exercise leaded to a decrease in depression and amelioration in metabolic syndrome. It is also probable that depression decrease as an effect of 3-month aerobic exercise relate with IL-6 decrease.

Background: Radical prostatectomy is the preferred treatment for prostate cancer, and sexual dysfunction is one of its complications. Various causes, including ischemic heart disease, diabetes, and cigarette smoking, can also cause sexual dysfunction in healthy people. Concurrent study of these cardiovascular risk factors with Surgery on the degree of sexual dysfunction in any study in Iran was not performed. The purpose of this study was to compare the risk factors of ischemic cardiovascular disease in locally diagnosed prostate cancer patients with and without sexual dysfunction after radical prostatectomy. Methods: In this longitudinal study, 96 patients underwent radical prostatectomy from 103 patients. The presence of risk factors for cardiovascular disease including cigarette smoking, diabetes, hypercholesterolemia, hypertention, history of heart attacks were asked from patients. Electrocardiogram findings, echocardiography, Exercise test and cardiac thalium scan were investigated by a cardiologist. Sexual function status of patients before and after 6 months of surgery was evaluated by Persian IIEF questionnaire. The qualitative variables of the frequency of reporting and comparing them were done using Fisher's exact test and Chi-square test. Subsequently, all data were analyzed with spss version 19. Results: The mean age of the patients was 63. 37 ± 7. 9 years. Patients with and without sexual dysfunction were 22 (22. 9%) and 74 (77%), respectively. The number of cardiovascular risk factors was statistically significant between the two groups with and without sexual dysfunction (P = 0. 001). 84 patients were tested for exercise and 12 patients underwent cardiac thalium scan. Of the 84 patients, 32 (40. 7%) were positive for the test, 52 (59. 3%) were negative. Comparison of the IIEF score in two groups was statistically significant (p = 0. 003). Conclusion: According to the results of this study, the risk factors of cardiovascular diseases and bad cardiovascular disease in patients undergoing radical prostatectomy surgery can affect the sexual potency of patients after surgery.

Background: Coronary Artery Disease (CAD) caused by atherosclerosis, Studies have shown that there are anumber of factors which are closely related to the development and progression of CAD that include Cellularbinding molecules like Plasminogen Activator Inhibitor-1 (PAI-1), multiple cardiac risk factors and hemostasis. Inthe present study we made an attempt to evaluate the association of PAI-1 4G/4G polymorphism and fibrinolysismarkers example PAI-1 with CAD. Methods: In this study, 140 individual, including 70 subjects as patient group and 70 subjects in the controlgroup were considered. Blood samples were obtained from all participants, genomic DNA was extracted and the4G/4G polymorphism of PAI-1 was amplified using specific primers. Polymorphism in the-675 position inpromoter of PAI-1 was detected by PCR-RFLP method. Serum levels of PAI-1 in the samples were measured byELISA. Results: Level of PAI-1 serum was significantly different between the two groups. PAI-1 genotype distributionin this case is the frequency of genotype 4G/4G in the patient group compared with the control group had higher. PAI-1 in patients who had genotype 4G, have a higher level compared to homozygous 5G (p-value=0. 01). Significant differences between serum level of PAI-1 and PAI-1 gene polymorphism with the risk of CAD wasobserved. Conclusion: The 4G/4G polymorphism of PAI-1 gene is a useful marker for fibrinolytic activity. Thispolymorphism due to increased in plasma level of PAI-1 which causes defects in fibrinolytic activity so increasingthe occurrence of cardiovascular diseases.

Background: Menopause is one of the natural processes in women’ s life. Post-menopausal bleeding is the most common cause of elder women referred to gynecologic clinic. The aim of this study was to study the pathological evaluation of abnormal uterine bleeding among women referred to besa’ at hospital. Methods: This study is a descriptive study. The total number of 48 postmenopausal women with bleeding who referred to besa’ at hospital within one year was included. Patient’ s characteristics were registered with check list. Data was analyzed with SPSS16 and descriptive statistics. Results: The results showed that the average age was 58. 04 ± 6. 98 years. The most common of pathology finding (39. 6%) was endometrial atrophic. Other findings were hyperplasia (20. 8%), hormonal disorder ((14. 6%), polyps (12. 5%), endometrial cancer (2. 1%). Endometrial atrophic among patient with 48 to 59 years old were more common. In the age group 48 to 59 years, 3. 1% had cancer and 40. 6% had endometrial atrophy. Among patients who past 6-10 years of their menopause 6. 7% had cancer and 40% had endometrial atrophic. Patients with 6-10 child had 4. 8% cancer and 47. 6% endometrial atrophic. Conclusion: Pathologic findings in postmenopausal women could help diagnose and treat patients with bleeding.

Background: Arsenic is one of the toxic metals. And its accumulating in liver. The aim of this study was to evaluate the effects of arsenic on alkaline phosphatase activity and its high and low molecular isoenzymes as indexes for liver function. Methods: In this experiment 36 male Wistar rats were randomly allocated into six groups. In a short-term study animal were grouped as follow: group 1 control, group 2 and 3 received 40 and 80 mg/l as sodium. In a long-term period groups received half the dose of short-term period with oral administration. Blood samples were taken over a 15-day and 45-day period and serum enzyme alkaline phosphatase liver was measured and high and low molecular were isoenzymes were separated using with gel filtration chromatography technique the activity of low and high molecular weight alkaline phosphatase were measured by laboratory routine method. Results: The administration of four different doses of As sodium decreased the activity of serum total alkaline phosphatase compare to the control group. (P<0/05). and The activity of low and high molecular weight alkaline phosphatase 52% and 2% decreased compare to the control group. Conclusion: Arsenic is able to decrease the alkaline phosphatase and thus can make damage to hepatocyts.

Background: Polycystic ovary syndrome (PCOS) is a syndrome with complex endocrine and metabolicdisorders and also associated with endometrial changes. According to antioxidant and anti-inflammatory effects ofcurcumin, the aim of this study was to evaluate the effect of curcumin on histomorphometry of endometrium inpolycystic ovarian syndrome mice model. Methods: In this experimental study 28 mice were divided into 4 equal groups. Control, PCOS control andexperimental PCOS treated with curcumin (100 and 200 mg/kg, ip). PCOS was induced by a single intramuscularinjection of estradiol valerate into PCOS control group and experimental PCOS group. Curcumin wasintraperitoneally injected into experimental PCOS groups for 16 days. Saline solution was injected to the animals ofcontrol and PCOS control groups. At the end of treatment, the endometrial biopsies were stained with Hematoxylin-Eosin and pathological changes were examined. Data was analyzed using one-way ANOVA and Post Hoc Tukeystatistical tests (P<0. 05). Results: Compare to the control group, number of glands and thickness of endometrial significant decrease andthickness of epithelial cells and thickness of the endometrial glands epithelial cells significantly increase in PCOScontrol group (p<0. 05). Dose dependent injection of curcumin was significantly improved histological parameterscompare to the PCOS control group (P<0. 05). Conclusion: Dose dependent administration of curcumin improves the endometrial histological damages ofPCOS mice model.

Background: Stiffness and restricted ROM affect muscle balance and alignment. The purpose of this researchwas to study the effect of iliopsoas tightness on hip ROM, muscle strength and alignment of lumbopelvic region in11-14 years old adolescents. Methods: In this case-control study, 15 adolescents with iliopsoas tightness as experimental group, and 15healthy adolescents which matched based on age, height, weight, BMI, dominant leg and sport experienceparticipated voluntarily as control group. Universal goniometer (r=0. 85-0. 95) used for measuring ROM, flexibleruler (r=0. 82) for kyphosis and lordosis degree, handheld dynamometer (r=0. 98) for muscle strength and digitalphotos are used for pelvic tilt angle. Data analyzed using Independent t test, Pearson correlation coefficient and dCohen’ s effect size. Results: There were significant differences between passive and active hip extension ROM, lumbar lordosis, pelvic tilt, iliopsoas strength, gluteus maximus/iliopsoas strength between groups. While, there were no significantdifferences in results of active and passive hip flexion ROM, kyphosis, and strength of gluteus maximus, rectusfemoris and biceps femoris between groups. Also there were no significant correlations between lumbar lordosis andpelvic tilt with other variables in this study. Conclusion: Adolescents with iliopsoas tightness have limited hip extension ROM, greater pelvic tilt and lumbarlordosis and weaker iliopsoas strength in comparison to healthy counterparts. Iliopsoas stretching, correctiveexercises for hyper lordosis and increased pelvic tilt and iliopsoas strengthening training should be included infootball training programs.

Background: Aerobic exercise increases the production of free radicals. Grape seed extract has a high potentialin removing the free radicals. The aim of this study was to determine the effect of concurrent aerobic training andgrape seed extract on total antioxidant capacity and malondialdehyde in young men. Methods: In this study, 40 healthy non-athlete male with an average (age 22. 60± 0. 98 in years, weight76. 07± 5. 11 in kg and body fat 18. 06± 1. 64 in percent) randomly divided into four groups of training-supplement(n=10), training-placebo (n=10), supplement (n=10) and control (n=10). Before and after the intervention, weight, BMI, and body fat percentage, maximum oxygen consumption, total antioxidant capacity and malondialdehyde weremeasured. Results: The mean age, weight, and body fat were 22. 60± 0. 98 years, 76. 07± 5. 11 kg, and 18. 06± 1. 64 percent, respective) The results showed that concurrent aerobic training and grape seed extract significantly increased totalantioxidant capacity and reduced malondialdehyde in the training-supplement, training-placebo and supplementgroups, and in the control group was significantly increased malondialdehyde. Conclusion: The results showed that 8 weeks aerobic training and consumption of grape seed extract increasedtotal antioxidant capacity and reduced the malondialdehyde.

Background: Discharge against Medical Advice (DAMA) is a global problem with unpleasant consequences, mandating to conduct studies for its Predictors and outcome. This study aimed to investigate the reasons of DAMA from a general referral hospital. Methods: A cross-sectional descriptive study was conducted in Sina Hospital. A researcher-made questionnaire was used after determining its validity and reliability. All patients who wanted to DAMA, completed the questionnaire. The data was analyzed by SPSS 19, using descriptive and inferential statistics. Results: DAMA was more seen within men, married, native, and under diploma patients with age range of 19 to 39 years. Prolongation of hospital stay (13. 2%), other hospital staff’ s suggestion (6. 8%) and dissatisfaction with the facilities (12. 3%) were among the main reasons for discharging. The reasons of DAMA had only significant relationship with hospital wards. Conclusion: Improvement of training, providing innovate facilities for young people, providing more advanced facilities and equipment, and continuing the necessary treatment as outpatient are important factors that must be prepared in order to decrease the rate of DAMA.

Background: Quantitative Electroencephalography (QEEG) is a useful tool to identify and investigate thedifference in the brain activity of patients. The aim of the present investigation was the comparison of Differencein brain activity patterns in children with different subtypes of epilepsy and children with attention deficithyperactivity disorder. Methods: The current investigated population included all of ADHD and epilepsy children that were visitedby psychotherapists and neurologists in Tabriz in 2014. 72 children (37 ADHD children and 35 epilepsy children)were selected through aimed sampling method with clinical interview by psychotherapists, neurologists and also byusing children pathological symptom scale(CSI-4). The brain activity patterns in each group were recorded byQEEG and were compared with each other. Results: There was a significant difference between absolute power of the delta (p<0/001) theta (p<0/05), alpha2(p<0/05) and beta1 bands (p<0/05) in epilepsy and ADHD groups; but the difference between alpha1 (p<0/05), beta2 (p<0/05) and beta3 (p<0/05) bands in two groups was not significant. Conclusion: There was a difference between brain activity patterns in children with subtypes of epilepsy andchildren with attention deficit hyperactivity. So, using QEEG for exact diagnosis is recommended.

Background: The aim of this study was to evaluate the memory problems in patients with obsessive-compulsivedisorder (checking, washing and mixing). Methods: 45 patients with obsessive-compulsive (15 checking and 15 washing and 15 combined) and 30 casesas control group (n = 15 as generalized anxiety disorder, and 15 normal subjects) were selected. Thoughts andactions obsessive-compulsive using the scale Obsessive-Compulsive Inventory (MOCI), Yale-Brown andpsychiatric interview. In this study, subjects' memory two word lists (recalling list and browse using signrecognition) that utilizes computers were provided, were compared between two groups. Results: Patients with OCD had a significant difference in terms of recognition memory and reminder usingsymptoms compared with normal control group. Conclusion: According to the psychological theories the memory problems in patients with OCD, particularly inthe context of cognitive-behavioral therapy seems to be explained and patients generally suffer from memoryimpairment.