The present study assesses the predictive role of Gardner's multiple intelligence components in academic achievement and academic discipline choices among high school students. 120 second grade female students (mean age 15) were selected randomly from a high school in Tehran. All subjects completed the Gardner's Multiple Intelligence Scale, the subjects' average total academic scores were also recorded, as the index of their academic achievement. Using regression analysis, one way ANOVA and Post-hoc tests, the results revealed: Students in mathematics' group were higher in logical-mathematical intelligence, in comparison with students in art and humanities groups, but there was no significant difference between mathematics and experimental science students. On the other hand, visual-spatial intelligence was higher among art students, in comparison with other students. Finally, mathematics students had higher verbal-linguistic intelligence, in comparison with art students. In general the research outcomes emphasize on the relationship between some of the components of the multiple intelligence, academic discipline choices, and academic achievement.