Introduction: The aim of this study was to evaluate the role of periodontal therapy on the improvement of metabolic control in diabetic patients.Materials and Methods: 10 diabetic patients with NIDDM (9 female and 1 male) with poor metabolic control (mean HbA1C = 11.1%), and mean age of 43.7 yrs. And mean diabetes duration of 7.4 yrs. All affected with moderare to severe chronic adult periodontitis were selected. The treatment included of scaling and root planning, extraction of hopeless teeth and periodontal flap surgery. The clinical measurements included of probing depth, clinical attachment level, plaque levels and bleeding on probing which were obtained at baseline as well as 18 weeks post treatment. Moreover, glycosylated hemoglobin (HbA1C) was measured at baseline and weeks 18 and 26. In addition, body mass index was measured at baseline and week 26.Results: Significant improvement was observed in clinical parameters between weeks 0 and 18, whereas no significant difference was observed in HbA1c of weeks 0, 18, and 26. However, a slight reduction in HbA1C was observed in week 26 as compared with week 0. Moreover, no significant correlation was observed between HbA1c and clinical parameters.Conclusion: Above findings indicate that surgical periodontal treatment is successful in diabetic patients, but no significant improvement in their diabetic metabolic control following periodontal therapy and other unknown factors might be involved. Further investigations with longer follow-up durations are warranted.