Journal of Ilam University of Medical Sciences
Year:2014 | Volume:22 | Issue:5|Papers Count:25

Introduction: Tumor necrosis factor a (TN-F-a) is a potent cytokine, which is originally identified as a factor implicated in inflammatory and immunoregulatory actions and it plays a role in the development of obesity, insulin resistance, and probability of type 2 diabetes. The objectives of the present study were to evaluate the association of -308 TNF-a promoter polymorphism with Type 2 Diabetes Mellitus.Materials & Methods: In all, 173 patients with T2DM and 173 normoglycemic subjects were included in this study. All subjects were genotyped using polymerase chain reaction-restriction fragment length and allelic frequencies were then analyzed in each group. Serum lipids, fasting glucose, fasting serum insulin, HOMA-IR, and H-bA1c levels were determined by conventional methods. Data was analyzed using SPSS software.Findings: The allelic frequency of the ‘A’ allele, was significantly different between case and control groups (P=0.006). Also, the genotype frequencies showed a significant difference in GA genotype between case and control individuals (OR=3.67, 95% CI=1.61-8.35, P=0.002). Similarly, the 308 TNF-alpha was found to be significantly associated with T2DM (OR=3.65, 95% CI=1.66-8.02, P=0.001) for the dominant model. But, no significant association was observed for recessive model (P>0.05). Discussion & Conclusion: This is the first study performed in Kurdish ethnic group from West Iran. The findings of this study revealed that the allele and genotype frequency of GA variation had a significant difference between case and control groups. Also, the 308 TNFa was found to be significantly associated with T2DM for the dominant model.

Introduction: Self-treatment is a one of the main inevitable problems in remedy cycle. In Iran, self treatment is so common that h-as caused the excessive use of drugs in the country. Therefore, this study aimed at determing the influential factors on self-treatment in the boarding clinic of Abasabad city (Mazandaran province).Materials & Methods: This is a descriptive cross-sectional study carried out in 2013 and 300 individuals refering to the Abasabad’s clinic were selected randomly. Data was collected by a questionnaire as well as interviews and then the Chi-square test was used to analyze the data.Findings: Results of data analysis showed a significant relationship between the variables of age, gender, education and occupation of people under study and each of the questionaires’ items about the probable reasons of headstrong use of medicine and the selection of injection form (p value <0.05). We evaluated the relationship of exessive medicine use with matrimory status, gender, the effect of education and a-ccuption of people under study. It was found that self-treatment is used by 204 men compared to 96 women, 176 married as compured to 124 singles, 137 pre-university level compared to 82 granduates. In our study, the major common of exessive use of drugs were easy availability of drugs from drugstors without prescription (98%), available drugs at home or getting from others (96.7%), lack of awareness on the drugs’ complications (72.7%), and give little atttention to diseases by the individual (72.7%).Discussion & Conclusion: In order to increase individuals awareness and performance, especial educational programms should be designed and presented to people via various educational methods and procedures. Self-treatment is itself neither good nor bad. Policy makers should do interventions in both micro and macro levels to decrease inappropriateuse of medicines. The interventions include: Restrictingeasy access to medicines especially harmful and dangrous medicines; Instruction on how to use and maintain medicine to patient by physician and pharmacist; General training of society for rational use of medicines and limiting the number and type of medicines stored at home; Elevation the quality of sanitary and treatment services and increasing the access of society to service presentation system. The above mentioned are very helpful in our study for decreasing obtained preferences regarding the obstinate use of medicines.

Introduction: Research has shown that consumption of calcium and iron supplements during pregnancy can prevent some problems in mother and embryo. The aim of this study was to determine the correlation between consumption of calcium, iron and multivitamin supplements and dental status in post partum mothers.Materials & Method: This research was a cross-sectional analytical-descriptive study with cluster sampling. The study sample included 150 pregnant women in their end phase of pregnancy from Shahid Mostafa Khomini and Hazrate Zeinab hospitals in Tehran. The study was completed from November 2010 to April 2011. Data were collected in 24 to 72 hours post partum. Demographic and supplements consumption data were recorded in a prepared checklist. The numbers of decayed, Missed and Filled teeth (DMFT index) were registered in the post partum. To analyze the data, Spearman correlation coefficient and Linear variance statistical tests were used.Findings: The correlation between consumption of iron supplement and DMFT was significant (P<0.001). A direct relationship was found between the consumption of iron supplement with DMFT (r=-0.33). The correlation between the consumption of calcium supplement and DMFT was significant (P<0.001). An indirect relation-ship was found between the consumption of calcium supplement with DMFT (r=0.42). The correlation between the consumption of multivitamin supplement and DMFT was not significant (P=0.09). There was not a direct relationship between the consumption of multivitamin supplement with DMFT (r=0.18). Discussion & Conclusion: Consumption of calcium supplement during pregnancy keeps teeth heal-thy. Therefore consumption of calcium supplement during pregnancy is recommended for presserveng mothers’ dental health status.

Introduction: Today, we are seeing change in the manufacturing process of mechanisms as a multi-purpose device with the dramatic growth of technology. It both helps in saving space and the cost of the product decreases considerably. Today, due to the cost of providing places for jobs, smaller and more compact multifunctional devices are designed. The proposed device is a du-al-use Laboratory Mixer. This device is designed for mixing liquid with determined viscosity, which has various options to enhance the quality and comfort of the operator.Materials & Methods: The device uses a combination of two methods while the process of mixing is separate in other devices, i.e. the mixer device is either radial or oscillating. One of the importing points in the design of the device is that both systems are combined in one device and it is equipped with control and timing speed system. So far, the roller or Rocker device have not been made and designed in Iran and they are built for the first time. Their main use is for professional mixing experiments in the laboratory of Immunology and medical diagnostics.Findings: The results of the electrical and mechanical performance of the device are acceptable according to the inventions used in various parts and it is economical.Discussion & Conclusion: We could significantly reduce blood clots while it is mixing up by designing the angle of the device. This problem is the result of blood into the vial with the vial cap that causes the so-called "lysis". Another achievement of this device is the combining of both the roller and Rocker devices which provides new mixing methods in the lab for operator.

Introduction: Emotional intelligence and personal style (sociotropy and autonomy) are important factors in predicting couples marital satisfaction. The present study aimed to determine the predictive power of personal style (Autonomy and Sociotropy) and Emotional intelligence in predicting couple's satisfaction.Materials & Methods: This research is a cross sectional study that used multiple relationship in regression context. The study population consisted of all couples referring to counseling centers of Zabol and the sample was 100 Couples referring to counseling centers. Data was collected using Enriches marital satisfaction questionnaire, Robins Personal Style Inventory and Bar on EQ questioner. Stepwise regression analysis was used to analyze the data and evaluate the predictive role of each of the variables.Findings: Results of the regression analysis showed that personal style and emotional intelligence have significant roles in predicting marital satisfaction of men and women when used both alone and in combination.Discussion & Conclusion: Couples’ marital satisfaction can be predicted using personal style (sociotropy and autonomy) and therefore they should be paid high attention while choosing a spouse and in family counseling.

Introduction: The aim of this study is to determine the effectiveness rate of two methods of dialectical behavior therapy and cognitive behavior therapy on the improvement of impulsive behavior symptoms of patients suffering from major depressive disorder showing a tendency to suicide.Material & Methods: This is a semi experimental study with two experimental groups (dialectical behavior therapy and cognitive behavioral therapy) and a control group. The population included all patients with major depressive disorder with impulsive behaviors association with thoughts of suicide who referred to psychological service center of Hamedan in the spring of 2013. The study sample included 21 patients with major depressive disorder and suicidal thoughts that had the entry criteria. The instruments included a constructed cognitive interview based on DSM, 2000; Bartlett Impulsive Test, 1994 & Beck suicide Tendency 1999 and the aim was to instruct dialectical behavior therapy and cognitive behavior therapy.Findings: Findings showed that dialectical behavior therapy was more effective than cognitive behavior therapy in patients suffering from basic (major) depression showing a tendency to suicide.Discussion & Conclusion: In domain therapy and dealing with the depressed patients, the dialectical behavior therapy seems so efficacious and encouraging for those who are in critical situation and have a tendency to suicide.

Introduction: Diabetes is a chronic disease that has widespread effects on individual and social performance. The purpose of this study was to compare the quality of life in patients with diabetes type 2 and non-diabetic individuals.Materials & Methods: The design of this research was ex-post facto. The sample consisted of all patients with diabetes type 2, who were members of Diabetic Association in the city of Ahvaz in 1390. The sample was selected by available sampling method. Among the patients who referred to the Diabetic Association,  50type 2 diabetic patients and 50 non-diabetic relatives of clients who were matched for sex and education were selected. Then, the Quality of life Questionnaire was distributed between these two groups. The collected data were analyzed using Analysis of Variance (ANOVA) and Multivariate Variance Analysis Method (MANOVA).Findings: Results indicated that there was a significant difference in quality of life between the two groups (p<0.001). Also, there was a significant difference between groups in all aspects of quality of life except social environment.Discussion & Conclusion: Diabetes is a chronic disease that affects patients' quality of life.

Introduction: Fatigue is an unpleasant symptom including a spectrum from feeling weak to becoming fatigue which interferes in individuals’ abilities in doing performance. There is no valid and reliable instrument to measure instructors’ fatigue in Iran. Therefore, this study aimed to translate and psychometrically evaluate “Multidimensional Symptoms Fatigue Inventory-Short Form”.Materials & Methods: This descriptive study was conducted among instructors in faculty of Nursing and Midwifery in The-ran. The questionnaire was completed by faculty instructors who were 140 individuals. “Multidimensional Symptoms Fatigue Inventory-Short Form” was translated then the content validity index, face and concurrent validity were measured. Meanwhile, reliability was evaluated by internal consistency and test re-test after two weeks.Findings: The content validity index of “Multidimensional Symptoms Fatigue Inventory-Short Form”, was 79.2 on relevance, 82.5 on clarity and 79.7 on simplicity, respectively. Face validity of the scale was approved according to experts’ opinions. Concurrent validity of “Multidimensional Symptoms Fatigue Inventory-Short Form”, with “Fatigue Severity Inventory” was measured and the correlation value was 0.77. Cronbach’s alpha of the scale was 0.91 and the reliability was 0.82 through test re-test method.Discussion & Conclusion: The “Multidimensional Symptoms Fatigue Inventory-Short Form” is a valid and reliable scale for measuring instructors’ fatigue in Iran.

Introduction: Extended-spectrum beta-lactamases (ESBLs) make some bacteria resistance to broad spectrum beta-lactam antibiotics. The aim of the present study was to evaluate the antibiotic resistance of clinical isolates of Pseudomonas aeruginosa in Mashhad and to detect CTX-M type extended-spectrum beta-lactamase among them.Materials and Methods: Clinical isolates of P. aeruginosa were collected from different samples (wound, urine, ear, lung, peritoneal fluid and other body fluids) of hospitalized patients in Mashhad in 2013. The antibiotic susceptibility was examined by disc diffusion method and Kirby-Bauer standards. The frequency of ESBL producing strains was determined via the combined disk method. After DNA extraction, the existence of blaCTX-M gene was detected by polymerase chain reaction (PCR) using specific primers.Findings: All isolates were resistance to ceftizoxime, cefoxitin and oxacillin. Resistance to ciprofloxacin, gentamicin, imipenem, piperacillin and cotrimoxazole was 45.31%, 48.44%, 45.31%,  43.75and 98.44%, respectively. A large percentage of ESBL-producing isolates compared with ESBL-non producers were resistant to cotrimoxazole, gentamicin, and piperacillin and the difference for gentamicin was significant. Out of 64 clinical isolated bacteria, 8 (12.5%) isolates were beta- lactamase producers and none of them were positive for blaCTX-M type ESBL.Discussion and Conclusions: Results of this study showed that however resistance of clinical isolates of P. aeruginosa to beta-lactam antibiotics was high in our community, but this resistance was not related to prevalence of blaCTX-M gene among isolated strains. Antibiotic resistance among these isolates could be associated with other types of beta-lactamases.

Vitamin K2 (Menaquinone-4), a derivative of vitamin K in the body is synthesized by intestinal bacteria. This vitamin is present at a higher concentration in the brain more than the other tissues. There is a potential ability for conversion of vitamin K derivatives to the type of K2 in the body. Vitamin K2 in turn is the main form of the vitamin K in the nervous system.These all together are indicating the importance of the functions of this vitamin in the central nervous system. Some of them are including its importance in the process of myelin synthesis and development of the nervous system. Vitamin K2 is known as one of the factors involved in the inflammatory processes. Actually vitamin K2 is associated with inflammation, pain, Alzheimer's, osteoporosis and some types of cancers. Regard to the probable role of vitamin K2 in the treatment of many human diseases that today have fallen within the biggest human concerns (such as cancer and neurodegenerative diseases), vitamin K2 is hoped to be considered in new research as an effective strategy for prevent or treatment of such diseases with minimum possible side effects.

Introduction: Considering the importance of spiritual interventions in the treatment of mental problems, the aim of this research was to investigate the effectiveness of cognitive therapy based on religious beliefs on death anxiety, social adjustment and mental well-being in cancer patients.Materials & Methods: This research was a semi-experimental study with pre/post test and a control group design. 30 cancer patients were selected through convenient sampling method as the sample group in Arezo Charity Institution in Parsabade Mogan city (N=300). The instruments used in this research were Mental Well-being and Social Adjustment and Death Anxiety Scales. The participants in the experimental group were under cognitive therapy based on religious beliefs for 8 sessions each lasting 2 hours. For statistical examination, the analysis of covariance (MANCOVA) was used.Findings: Results showed that there was a significant difference between the mean score of pre-test and post-test of both experimental and control groups. The cognitive therapy based on religious beliefs decreased death anxiety scores and also increased the scores of social adjustment and mental well-being in the experimental group rather than the control group.Discussion & Conclusion: Due to the efficacy of cognitive therapy based on religious believes in cancer patients, we can benefit this method as a complementary therapy beside medical treatments and therefore use it to improve the mentioned psychological problems in these patients.

Introduction: Mental disorders play an important role in suicide occurrenceso that more than 90 percent of suicide victims are suffering from a mental disorder at the time of death. The present study aimed to determine the epidemiological aspects of suicide due tomentaldisordersin Ilam province.Material &Methods: Through a cross-sectional study, all records of suicide events either completed or attempts (n=5188) were investigated in Ilam province during 1993 to 2009. A Chi-square and multiple logistic regressions analysis was adopted to estimate the role of risk factors associated with suicide events due to mental disorders.Findings: In overall,  27.5%of suicides occurred due to mental disorders. The highest frequency of suicides due to mental dis-orders belonged to males (29.3%), individuals with and over 30 years old (33.2%), attempted suicide (28.3%), the year 1996 (44%) and the decade of 1990s (30.3%). The risk of suicide due to mental disorders was estimated to be (OR=0.85, CI=0.74-0.97) for females, (OR=2.42, CI= 1.79-3.26) for the year 1996, (OR=0.79, CI= 0.67-0.93) for completed suicide and (OR=0.82, 0.66-1.01) for the age group of 25 to 29 years old.Discussion &Conclusion: It is required to train people at risk including attempted suicides among males.

Introduction: ISO 14000 standards series can increase competitiveness, productivity, and hospitals’ credibility and reduce costs and lead environmental management systems into green hospitals with low impact on the environment. This study aims to determine solutions of meeting green hospital standards in Yazd educational hospitals based on ISO 14000 standards series in 2013.Materials and Methods: This research is an applied, descriptive study carried out in 2013. The study population included Yazd educational hospitals. Using a questionnaire, the required data were collected based on variables of environmental management system in hospitals. The content validity was approved regarding the design and quantification of instrument while reliability was confirmed by pre-test using Cronbah alpha Coefficient as 0.9314. The SPSS software (version 16.0) was used for statistical analysis.Findings: Based on results of this research, comparing ten variables on green hospital management in four Yazd educational hospitals with hypothetical average (3) using one sample t-test indicated that there is no significant difference among four educational hospitals (P=0.734 CI=95%). Furthermore, results of Kruskal Wallis test demonstrated a significant difference among the hospitals (P=0.035 CI=95%). Finally, HCA technique resulted in clusteringsimilar questions in line with their corresponding answers.Discussion and Conclusion: The findings of this research showed that inadequate attention to environmental strategies, inadequate environmental training, improper management of wastes, inadequate allocate-on of fund for the management of wastewater and emission of pollutants into the air are the most important obstacles in achieving green hospital standards in Yazd educational hospitals and developing management strategies and their implementation by continuous training seems essential.

Introduction: Based on previous studies, Plasma total sialic acid (TSA) of many diseases is known as an inflammatory marker. This study attempts to determine TSA levels in patients with pneumonia and introduce it as a perfect diagnostic marker for pneumonia.Materials & Methods: In this study,  30patients with pneumonia and 20 healthy controls participated. Plasma TSA values were estimated by Sydows method and Data were compared using t-test and ROC curve.Findings: Plasma levels of this marker showed a significant increase in the patient group compared to the control group (p<0.0001). There was a significant positive correlation between TSA concentration and age in patients (p<0.0001, r= 0.718). Area under ROC curve (AUC), diagnostic sensitivity and specificity of total sialic acid for detection of pneumonia were 1,  96.7and 100%, respectively.Discussion & Conclusions: According to the results, TSA has good sensitivity and specificity for the diagnosis of pneumonia and it can be used as a perfect diagnostic biomarker for this disease.

Introduction: RS67333 is the selective agonist of 5-HT4 and ACPA (Arachidonylcyclopropylamide) is the selective agonist of CB1. The aim of present study was investigate the bilateral injection effects of dorsal hippocampus (CA1) serotonergic system (Agonist of 5-HT4) on fear memory formation process induced by ACPA in mature male mice.Materials & Methods: 120 Male NMRI mice weighting 23-28 gr were put into control and experimental groups in our experiments. Fear conditioning task was used for conditioning of fear. 24 hours after training, we estimated the fear memory formation.Findings: Intraperitoneal administration of ACPA (0.005,  0.05and 0.5 mg/kg) causes impairment of fear memory and amnesia. Moreover, intra-CA1 injection of 5-HT4 receptor agonist (RS67333) (0.005,  0.05and 0.5 mg/mice) in highest dose impaired fear memory and induced amnesia in saline-treated mice, and increased the impairment of fear memory in ACPA-treated mice (P<0.05).Discussion & Conclusion: Serotonergic system (Agonist of 5-HT4) in the CA1 of hippocampus induced by ACPA interferes in the impairment of fear memory.

Introduction: Recently, investigating the effect of different training methods, especially high-intensity interval training, on risk factors of obesity has been dramatically expanded. Hence, the aim of this study was to investigate the effects of 12 weeks of low-volume high-intensity interval training and traditional continuous exercise training on adiponectin levels and lipids profile in obese young men.Material & Methods: The subjects of this study were 34 obese young men (age: 22.4±3.6 years, BMI: 32.98±2.4 kg/m2) that were randomly divided into three groups of low-volume high-intensity interval training (LVHIIT) (n=11), traditional continuous exercise training (TCET) (n=11) and control (n=12). Experimental groups trained 12-weeks and 3 times in a week. Control group subjects performed only their routine activities. For data analysis, one way ANOVA and paired t-test were used.Findings: The results showed that lipids profile and adiponctin resting levels improved significantly in experimental groups compared with pre-test values (p<0.05). Resting levels of adiponectin in LVHIIT group was significantly higher than in control group (p=0.037), but no differences were found between the experimental groups (p>0.05).Discussion &Conclusion: According to the profound differences in training volume of experimental groups, it is appeared that LVHIIT is comparable with TCET in terms of duration, and also reduces some of the risk factors of obesity.

Introduction: Sheng plant with the scientific name Tragopogon graminifolius (T. graminifolius), is used as a wound healer for wounds created in livestock such as sheep and goats in the traditional medicine of Bakhtiari and Lorestan regions ever since ancient times. Since this plant is used in wound healing of livestock by Bakhtiari nomads and as plant compounds do not have the complications of chemical treatments, this study used the T. gram inifolius extract for wound healing in Lewis race rats.Materials & Methods: The wound was made with puncher skin lesion in 45 male rats and they were randomly divided into 5 groups including control (no treatment), Sham (treated with petroleum jelly) and Experimental1 (exp1.8), experimental 2 (exp1.4), experimental 3 (exp1.2). Experimental groups were treated with 2.5 mg/kg,  5mg/kg and 10 mg/kg of Tragopogon extract. Wound healing percent, epidermis thickness, number of macrophages, fibroblasts and neutrophils were determined. Data were analyzed using unilateral variance analysis and results were stated based on (ANOVA) using SPSS 11 software and graphs plotted with Excel.Findings: There was a significant increase in wound healing, epidermis thickness, number of macrophages, fibroblasts and neutrophils in experimental groups (2 and 3) in comparison with the shame group (p<0.05).Discussion & Conclusion: Results of this study showed that the external use of T. graminifolius extract has wound healing effects on skin lesion.

Introduction: Myeloperoxidase (MPO) has an essential role in the promotion of ather-osclerosis andcoronary artery disease (CA-D). Therefore, this study explored the plasma level of this enzyme in relation to other traditional cardiovascular risk factors in patients with stable and unstable CAD as compared to control subjects.Materials & Methods: In this study,  30patients with stable CAD,  30patients with unstable CAD and 30 control subjects were selected based on angiography procedure. Plasma MPO was measured using an immunoassay method. High sensitivity C-reactive protein (hsCRP) level was determined by a latex-enhanced immunot-urb-id-imetric method. Plasma lipid and lip-op-rotein profiles (LDL-cholesterol, HDL-cholesterol, total cholesterol and triglycerides) were also determined by enzymatic methods. Other cardiovascular risk factors were also assigned through medical history and questionnaire.Findings: MPO and hsCRP levels were significantly higher in unstable CAD patients than stable CAD patients. Also, the amounts of these two biomarkers were higher in stable CAD patients than control subjects (P<0.01). In patients, MPO level had a significant relationship with hsCRP and the presence of CAD (P<0.01).Discussion & Conclusion: Elevated level of MPO was a positive independent predictor for the presence of CAD and its plasma levels can differentiate between unstable C-AD patients, stable CAD patients and control subjects and may have a diagnostic value.

Introduction: During inflammation, the inflammatory glycoprotein of pentraxin-3 (PTX3) is synthesized by endothelial cells, macrophages and myelogenous cells. This inflammatory glycoprotein plays a fundamental role in the process of atheros-clerosis and coronary artery disease (CAD). Moreover, this protein is predominantly re-marked in sclerotic lesions and may act as an independent prognostic factor in CAD compared with healthy subjects and its in-crease might bring about harsh consequences for CAD.Materials & Methods: In the present research,  30patients with unstable CAD,  30patients with stable CAD, and 30 healthy control subjects were studied based on angiographic findings. ELISA method was employed to determine the plasma level of PTX3. The concentration of the high-sensitivity C-reactive protein of plasma (hsC-RP) was assigned via a latex-enhanced immunoturbidimetric method. Plasma levels of HDL-cholesterol, LDL- cholesterol, total cholesterol and triglycerides were also measured by enzymatic methods. The condition of other cardiovascular risk-factors was determined by referring to individuals’ medical history and questionnaires.Findings: Using ROC curve with high sensitivity and specificity, the findings revealed that the levels of PTX3 and hsCRP were higher among patients with unstable CAD than patients with stable CAD (p<0.01). Furthermore, the levels of these two combinations were more among patients with stable CAD than control subjects (p<0.01). Among the patient groups, PTX3 had a significant relationship with hsCRP as well as the occurrence of CAD (p<0.01).Discussion & Conclusion: Inflammatory processes play a central role in the formation of atherosclerotic plaques in athero-sclerosis from the primary phase of starting defects in endothelial cells to the formation of mature atherosclerotic plaques and their subsequent rupture. The inflammatory glycoprotein of pentraxin-3 (PTX3) is basically remarked in sclerotic lesions. Among the CAD patients, the rupture of the fibrous cap on atherosclerosis plaque leads to the direct exposure of underlying thrombosis (clot-causing) sections of atherosclerosis plaque to blood flow which starts the water-fall activation of blood coagulation via attachment, activation and aggregation of platelets. Among unstable CAD patients, pentraxin-3 is freed from activated neutrophils by platelets and it seems that it increases at the end stage of heart failure but its level is lower in neutrophils of stable CAD and this factor is the agent cause of differ rentiation between stable CAD and unstable CAD. Moreover, physiological concentrate-on of this biomarker in plasma is 2ng/ml and the control subjects are specified based on this level of concentration. In other words, the increase in the plasma level of PTX3 may well act as a positive predictor for the presence of CAD, discriminate between stable CAD patients, unstable CAD patients and the control subjects and have a diagnostic value.

Introduction: Postural control is the body's innate capacity to maintain the center of gravity in the support limits. About the effects of spinal curvature on postural stability (balance), there are conflicting results and often have been considered change a special curvature only. The purpose of this study was to study postural control in individuals with sway back abnormalities. Methods: To conduct the present study, 35 subjects with sway back posture with the average of age 20.65±1.52 years, Weight 67.39±12.31 kg and height 171.93±6.84 cm and 35 normal people with the average of age 20.6±1.23 years, Weight 67.07±11.31 kg and height 171.81±7.77 cm were selected. Side view photography and calculate the sway angle was used to select subjects with sway back posture (>10). Other tools used in this study were as follows: photography and craniovertebral angle calculating for measuring the forward head displacement, dual inclinometer for measurement of kyphosis and lordosis. COP parameters were also measured by foot pressure distribution software. Pearson correlation coefficient and independent t-test in the significant level of P≤0.05 was used to analyze the collected data.Findings: No significant differences were observed between natural subject and subjects with sway back on the forward head angle (p=0.02), thoracic kyphosis (p=0.023), lumbar lordosis (p=0.017) and sway angle (p=0.001). There was significant difference between COP variables of the normal and sway back subjects (p=0.02). A significant relationship was observed between anterior - posterior COP displacement and forward head angle (r=0.2), thoracic kyphosis (r=0.29), lumbar lordosis (r=0.41) and lordosis, kyphosis ratio (r=0.53) (p≤0.05). Conclusion: As a result, it appears that the spinal abnormalities in the subjects with sway back posture can cause poor postural control.