The effect of eight weeks of interval training and quercetin nanoliposome supplementation on NF-κ, B and FGF-2 gene expression in the heart tissue of myocardial infarction rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Zaheri Abdehvand Samira; JALALI DEHKORDI KHOSRO; TAGHIAN FARZANEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES Year:2022 | Volume:24 | Issue:1 Page(s): 25-30

Download Full-Text

View:

105

Download:

Cites:

Information Journal Paper

Title

The effect of eight weeks of interval training and quercetin nanoliposome supplementation on NF-κ, B and FGF-2 gene expression in the heart tissue of myocardial infarction rats

Author(s)

Zaheri Abdehvand Samira | JALALI DEHKORDI KHOSRO | TAGHIAN FARZANEH | Issue Writer Certificate

Keywords

High-intensity interval training

Nuclear factor kappa B

Fibroblast growth factor-2

Quercetin supplementation

Myocardial infarction

Abstract

Background and aims: The activation of inflammatory reactions is essential immediately after the onset of myocardial infarction (MI). On the other hand, the path of inflammatory activators should be controlled to prevent the recurrence of MI. In this vein, the aim of this study was to examine the effect of eight weeks of interval training and quercetin nanoliposome consumption on nuclear factor kappa B (NF-κ, B) and fibroblast growth factor 2 (FGF-2) gene expression in the heart tissue of MI rats. Methods: In this experimental study, 30 male rats, aged approximately 6-8 weeks, were randomly divided into five groups including MI + training, MI + supplement, MI + training + supplement, healthy control, and MI. The MI was induced by the subcutaneous injection of isoprenaline hydrochloride at a dose of 80 mg/kg. Quercetin was daily administered at a dose of 0. 25 mg for 8 weeks, and interval training was performed 5 days a week. NF-κ, B and FGF-2 gene expressions were measured by the real-time polymerase chain reaction. Finally, data were analyzed using the one-way analysis of variance (ANOVA) and Tukey’, s post hoc tests (P < 0. 05). Results: Training significantly increased NF-κ, B gene expression in the MI+ training, MI + supplement, and MI + training + supplement groups (P = 0. 001) while significantly decreasing FGF-2 gene expression in the MI group (P = 0. 04). Conclusion: Interval training may prevent the negative effects of MI by reducing pro-inflammatory gene expression in the heart tissue, leading to improved cardiovascular function and the prevention of this disease.

Multimedia

No record.

Cites

References

Cite

APA: Copy

Zaheri Abdehvand, Samira, JALALI DEHKORDI, KHOSRO, & TAGHIAN, FARZANEH. (2022). The effect of eight weeks of interval training and quercetin nanoliposome supplementation on NF-κ, B and FGF-2 gene expression in the heart tissue of myocardial infarction rats. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 24(1), 25-30. SID. https://sid.ir/paper/1002748/en

Vancouver: Copy

Zaheri Abdehvand Samira, JALALI DEHKORDI KHOSRO, TAGHIAN FARZANEH. The effect of eight weeks of interval training and quercetin nanoliposome supplementation on NF-κ, B and FGF-2 gene expression in the heart tissue of myocardial infarction rats. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2022;24(1):25-30. Available from: https://sid.ir/paper/1002748/en

IEEE: Copy

Samira Zaheri Abdehvand, KHOSRO JALALI DEHKORDI, and FARZANEH TAGHIAN, “The effect of eight weeks of interval training and quercetin nanoliposome supplementation on NF-κ, B and FGF-2 gene expression in the heart tissue of myocardial infarction rats,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 1, pp. 25–30, 2022, [Online]. Available: https://sid.ir/paper/1002748/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops