EFFECT OF SINGLE DOSE OF DEXAMETHASONE ON NAUSEA, VOMITING AND DISCHARGE TIME FROM RECOVERY ROOM IN OUT-PATIENTS UNDERGOING ANORECTAL SURGERY

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PERVAIZ KAZEMI A.; KAMALIPOUR H.; MOHAMMADI S.

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Journal: JOURNAL OF MEDICAL RESEARCH (JMR) Year:2003 | Volume:1 | Issue:4 Page(s): 34-40

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Title

EFFECT OF SINGLE DOSE OF DEXAMETHASONE ON NAUSEA, VOMITING AND DISCHARGE TIME FROM RECOVERY ROOM IN OUT-PATIENTS UNDERGOING ANORECTAL SURGERY

Author(s)

PERVAIZ KAZEMI A. | KAMALIPOUR H. | MOHAMMADI S. | Issue Writer Certificate

Keywords

DEXAMETHASONEQ4

OUTPATIENT SURGERYQ4

RECOVERYQ4

ANORECTALQ4

Abstract

Background: As the expenses of patient hospitalization are high, most surgeons prefer to perform operations in out-patient departments. Many researchers have tried to find practical and scientific ways to shorten the RECOVERY stay time in order to prevent an abundance of patients in RECOVERY rooms after operations. Previous studies have shown that corticosteroids are useful in the control of nausea and vomiting as well as pain, which are all important factors in increasing RECOVERY staying time after operations. Patients and Methods: In this prospective double-blind study, the effect of a single dose of DEXAMETHASONE on RECOVERY staying time in a group of 80 patients who had undergone an ANORECTAL surgery was studied. The patients who were in ASA class I or II were randomly divided into two equal groups. The case group (Group A) consisting of 40 patients and the control group (Group B) had the same number of patients. All the patients received 0.03 mg/kg of midazolam and 0.1 mg/kg of morphine intravenously as premeditation (preanesthetics), after which 4 mg/kg of thiopental was used to induce anesthesia. After injection of preanesthetic drugs, the cases (Group A), received 8 mg of DEXAMETHASONE (2 ml) and controls (Group B) 2 ml of normal saline, intravenously. The maintenance of anesthesia was achieved using 50% of 02, 50% of N20 and 1% halothane via a mask. The RECOVERY staying time was regarded as the time from termination of anesthetic gases, until the patient could walk and drink. A RECOVERY nurse, who was blind to the study, recorded nausea, vomiting and pain. Results: The results showed that the injection of 8 mg of DEXAMETHASONE intravenously could effectively reduce nausea (p=0.007), vomiting and pain (p=0.002) after out-patient ANORECTAL surgeries and could also significantly decrease the RECOVERY staying time of patients postoperatively (p=0.001). Conclusion: It can be concluded that a single dose of intravenous DEXAMETHASONE during induction of anesthesia could shorten the RECOVERY staying time of patients postoperatively.

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APA: Copy

PERVAIZ KAZEMI, A., KAMALIPOUR, H., & MOHAMMADI, S.. (2003). EFFECT OF SINGLE DOSE OF DEXAMETHASONE ON NAUSEA, VOMITING AND DISCHARGE TIME FROM RECOVERY ROOM IN OUT-PATIENTS UNDERGOING ANORECTAL SURGERY. JOURNAL OF MEDICAL RESEARCH (JMR), 1(4), 34-40. SID. https://sid.ir/paper/105785/en

Vancouver: Copy

PERVAIZ KAZEMI A., KAMALIPOUR H., MOHAMMADI S.. EFFECT OF SINGLE DOSE OF DEXAMETHASONE ON NAUSEA, VOMITING AND DISCHARGE TIME FROM RECOVERY ROOM IN OUT-PATIENTS UNDERGOING ANORECTAL SURGERY. JOURNAL OF MEDICAL RESEARCH (JMR)[Internet]. 2003;1(4):34-40. Available from: https://sid.ir/paper/105785/en

IEEE: Copy

A. PERVAIZ KAZEMI, H. KAMALIPOUR, and S. MOHAMMADI, “EFFECT OF SINGLE DOSE OF DEXAMETHASONE ON NAUSEA, VOMITING AND DISCHARGE TIME FROM RECOVERY ROOM IN OUT-PATIENTS UNDERGOING ANORECTAL SURGERY,” JOURNAL OF MEDICAL RESEARCH (JMR), vol. 1, no. 4, pp. 34–40, 2003, [Online]. Available: https://sid.ir/paper/105785/en

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