EFFECTS OF L-CARNITINE SUPPLEMENTATION ON SERUM LIPIDS AND APOPROTEINS IN HEMODIALYSIS PATIENTS WITH LP(A) HYPERLIPOPROTEINEMIA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHAKERI AZAM; TABIBI H.; OSAREH SH.; NEYESTANI T.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY Year:2007 | Volume:2 | Issue:2 Page(s): 1-14

Download Full-Text

Persian Verion

View:

789

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF L-CARNITINE SUPPLEMENTATION ON SERUM LIPIDS AND APOPROTEINS IN HEMODIALYSIS PATIENTS WITH LP(A) HYPERLIPOPROTEINEMIA

Author(s)

SHAKERI AZAM | TABIBI H. | OSAREH SH. | NEYESTANI T. | Issue Writer Certificate

Keywords

L-CARNITINEQ4

HEMODIALYSISQ4

LP(A)-HYPERLIPOPROTEINEMIAQ4

LIPIDSQ4

APOPROTEINSQ4

Abstract

Background and objectives: Lipid abnormalities, especially high serum Lp(a) concentrations, are one of the major causes of cardiovascular diseases in HEMODIALYSIS patients. The present study was designed to investigate the effects of L-CARNITINE supplementation on serum LIPIDS and APOPROTEINS in HEMODIALYSIS patients with Lp(a) hyperlipoproteinemia.Materials and methods: The study was a randomized clinical trial in which 36 hyper Lp(a) HEMODIALYSIS patients (23 males and 13 females) with serum Lp(a) more than 30 mg/dl were randomly assigned to receive either a daily oral carnitine supplement of 1000mg (carnitine group) or no supplement (control group) for 12 weeks. At the baseline and the end of the period 5ml blood were collected after a 12 to 14-hour fast from each patient before dialysis and serum free carnitine, triglyceride, total cholesterol, HDL-C, LDL-C, apoAI, apoB100, Lp(a), IL-6 and albumin were measured. Results: As compared to the initial values, the mean serum free carnitine concentration increased significantly in the carnitine group at the end of the period (P<0.001), while serum triglyceride (P<0.05), total cholesterol (P<0.001) and IL-6 (P<0.001) decreased significantly. No significant changes were observed in the serum concentrations of free carnitine, triglyceride, total cholesterol and IL-6 in the control group. In addition, there were no significant differences between the 2groups as regards mean changes of the serum HDL-C, LDL-C, apoAI, apoB100, Lp(a), and albumin levels.Conclusion: The results of the present study indicate that an L-CARNITINE supplement has no effect on serum Lp(a) concentration in HEMODIALYSIS patients with Lp(a) hyperlipoproteinemia, but it may be effective in preventing cardiovascular diseases by reducing serum triglyceride and total cholesterol concentrations in these patients.

Cites

No record.

References

No record.

Cite

APA: Copy

SHAKERI, AZAM, TABIBI, H., OSAREH, SH., & NEYESTANI, T.. (2007). EFFECTS OF L-CARNITINE SUPPLEMENTATION ON SERUM LIPIDS AND APOPROTEINS IN HEMODIALYSIS PATIENTS WITH LP(A) HYPERLIPOPROTEINEMIA. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, 2(2), 1-14. SID. https://sid.ir/paper/121236/en

Vancouver: Copy

SHAKERI AZAM, TABIBI H., OSAREH SH., NEYESTANI T.. EFFECTS OF L-CARNITINE SUPPLEMENTATION ON SERUM LIPIDS AND APOPROTEINS IN HEMODIALYSIS PATIENTS WITH LP(A) HYPERLIPOPROTEINEMIA. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY[Internet]. 2007;2(2):1-14. Available from: https://sid.ir/paper/121236/en

IEEE: Copy

AZAM SHAKERI, H. TABIBI, SH. OSAREH, and T. NEYESTANI, “EFFECTS OF L-CARNITINE SUPPLEMENTATION ON SERUM LIPIDS AND APOPROTEINS IN HEMODIALYSIS PATIENTS WITH LP(A) HYPERLIPOPROTEINEMIA,” JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, vol. 2, no. 2, pp. 1–14, 2007, [Online]. Available: https://sid.ir/paper/121236/en

Related Journal Papers