THE EFFECT OF SUB-MINIMUM INHIBITORY CONCENTRATION (S-MIC) OF CIPROFLOXACIN & AMPICILLIN ON HEMOLYSIN ACTIVITY OF ESCHERICHIA COLI

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HAVAEI SEYED ASGHAR; SATARI MORTEZA; OSHAGHI M.; HASHEMI SHAHRAKI A.A.R.

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Journal: IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY Year:2008 | Volume:2 | Issue:1 Page(s): 53-58

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Title

THE EFFECT OF SUB-MINIMUM INHIBITORY CONCENTRATION (S-MIC) OF CIPROFLOXACIN & AMPICILLIN ON HEMOLYSIN ACTIVITY OF ESCHERICHIA COLI

Author(s)

HAVAEI SEYED ASGHAR | SATARI MORTEZA | OSHAGHI M. | HASHEMI SHAHRAKI A.A.R. | Issue Writer Certificate

Keywords

E. COLIQ3

HAEMOLYTIC ACTIVITYQ4

AMPICILLINQ2

CIPROFLOXACINQ4

Abstract

Background and objectives: Sub-minimum inhibitory concentration (S-MIC) can induce changes in morphology, virulence factors and biochemical properties of bacterial pathogens. The goal of this study is to determine the Sub-MIC effect of CIPROFLOXACIN and AMPICILLIN on the haemotytic activity of E. COLI.Material and Methods: Two clinical isolates of E. COLI with high heamolytic activity was selected. Changes in HAEMOLYTIC ACTIVITY of the isolates were assessed after exposing them to MIC and Sub-MIC of CIPROFLOXACIN and AMPICILLIN.Results: CIPROFLOXACIN decreased HAEMOLYTIC ACTIVITY at 1/2, 1/4 and 1/8 Sub-Mic, whereas AMPICILLIN showed no effect on HAEMOLYTIC ACTIVITY.Conclusion: We conclude that Sub-MIC concentrations of CIPROFLOXACIN decreased the HAEMOLYTIC ACTIVITY of E. COLI, wherease AMPICILLIN had no such effect.

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APA: Copy

HAVAEI, SEYED ASGHAR, SATARI, MORTEZA, OSHAGHI, M., & HASHEMI SHAHRAKI, A.A.R.. (2008). THE EFFECT OF SUB-MINIMUM INHIBITORY CONCENTRATION (S-MIC) OF CIPROFLOXACIN & AMPICILLIN ON HEMOLYSIN ACTIVITY OF ESCHERICHIA COLI. IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY, 2(1), 53-58. SID. https://sid.ir/paper/132663/en

Vancouver: Copy

HAVAEI SEYED ASGHAR, SATARI MORTEZA, OSHAGHI M., HASHEMI SHAHRAKI A.A.R.. THE EFFECT OF SUB-MINIMUM INHIBITORY CONCENTRATION (S-MIC) OF CIPROFLOXACIN & AMPICILLIN ON HEMOLYSIN ACTIVITY OF ESCHERICHIA COLI. IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY[Internet]. 2008;2(1):53-58. Available from: https://sid.ir/paper/132663/en

IEEE: Copy

SEYED ASGHAR HAVAEI, MORTEZA SATARI, M. OSHAGHI, and A.A.R. HASHEMI SHAHRAKI, “THE EFFECT OF SUB-MINIMUM INHIBITORY CONCENTRATION (S-MIC) OF CIPROFLOXACIN & AMPICILLIN ON HEMOLYSIN ACTIVITY OF ESCHERICHIA COLI,” IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY, vol. 2, no. 1, pp. 53–58, 2008, [Online]. Available: https://sid.ir/paper/132663/en

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