COMPARISON OF THE EFFECT OF SINGLE AND TRIPLE DOSE OF ANTIBIOTIC PROPHYLAXIS ON POST CESAREAN SECTION INFECTION

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EFTEKHARI N.; SALARI Z.

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Title

COMPARISON OF THE EFFECT OF SINGLE AND TRIPLE DOSE OF ANTIBIOTIC PROPHYLAXIS ON POST CESAREAN SECTION INFECTION

Author(s)

EFTEKHARI N. | SALARI Z. | Issue Writer Certificate

Keywords

PROPHYLAXISQ3

ANTIBIOTICQ4

CESAREANQ3

INFECTIONQ3

Abstract

Following CESAREAN INFECTION is one of the main complications, and ANTIBIOTIC prophylaxy is an important protective factor in reduction of post operational INFECTIONs. The aim of this study is to compare the prophylactic effect of single dose ampicillin to triple dose ampicillin following the operation. This prospective randomized clinical trial lasted from Jun 1994 till January 2000. In this double blind randomized clinical trial a total of 242 women were prophylactic ally treated with ampicilin following the CESAREAN section. The subjects were divided equally into three groups; group one received three doses andthe second group received a single dose of the drug following clamping of the cord. The average age of the women, gestation age, and the duration of the surgery were the same. The most common reason for the c-section was the previous history of having a c-section, and the most common type of incision was fannensteil. No significant difference was observed in wound INFECTION between the first and second group. (3.3% compared to 9.9%), although endometritis was higher in the group one (1.7%) than in the second group (0.8%). 8.2% in the first group and 9.9% in the second group showed febrile reactions, however the difference was not significantly different. The results indicates that there is no significant difference observed in INFECTION rate and febrile reactions. Therefore a single dose of ampicillin is recommended, for prophylactic purpose following CESAREAN section.

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APA: Copy

EFTEKHARI, N., & SALARI, Z.. (2000). COMPARISON OF THE EFFECT OF SINGLE AND TRIPLE DOSE OF ANTIBIOTIC PROPHYLAXIS ON POST CESAREAN SECTION INFECTION. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, 7(4), 167-172. SID. https://sid.ir/paper/220/en

Vancouver: Copy

EFTEKHARI N., SALARI Z.. COMPARISON OF THE EFFECT OF SINGLE AND TRIPLE DOSE OF ANTIBIOTIC PROPHYLAXIS ON POST CESAREAN SECTION INFECTION. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2000;7(4):167-172. Available from: https://sid.ir/paper/220/en

IEEE: Copy

N. EFTEKHARI, and Z. SALARI, “COMPARISON OF THE EFFECT OF SINGLE AND TRIPLE DOSE OF ANTIBIOTIC PROPHYLAXIS ON POST CESAREAN SECTION INFECTION,” JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, vol. 7, no. 4, pp. 167–172, 2000, [Online]. Available: https://sid.ir/paper/220/en

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