ANTI CANDIDAL ACTIVITY OF ECHINOPHORA PLATYLOBA AGAINST CANDIDA ALBICANS AND COMPARISON WITH AMPHOTRICIN

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MAHBOUBI MOHADESEH; AVIZHGAN M.; DARABI MAHDI; KASAEIAN NAZILA

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Journal: Journal of Medicinal Plants Year:2009 | Volume:8 | Issue:30 Page(s): 36-43

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Information Journal Paper

Title

ANTI CANDIDAL ACTIVITY OF ECHINOPHORA PLATYLOBA AGAINST CANDIDA ALBICANS AND COMPARISON WITH AMPHOTRICIN

Author(s)

MAHBOUBI MOHADESEH | AVIZHGAN M. | DARABI MAHDI | KASAEIAN NAZILA | Issue Writer Certificate

Keywords

AMPHOTRICIN BQ3

ECHINOPHORA PLATYLOBAQ3

EXTRACTQ3

DERMATOPHYTESQ3

YEASTQ3

Abstract

Background & Aim: Increasing usage of medical plants for medical treatment made for this branch of complementary medicine a unique place. Methods: This study evaluated the anti candidal activity of ECHINOPHORA PLATYLOBA EXTRACTs and AMPHOTRICIN B against Candida albicans by micro broth dilution assay and Disc diffusion method. The synergism between AMPHOTRICIN B and ethanolic EXTRACT of E. platyloba was assessed by micro broth dilution assay. AMPHOTRICIN B was diluted at concentration between 16-0.125mg ml-1. Each tube contains 0.78 mg ml-1 E. platyloba EXTRACT. The MIC and MBC of AMPHOTRICIN B was recorded. Results: The MIC and MBC of ethanolic EXTRACT of E. platyloba and AMPHOTRICIN B against C. albicans were 3125, 1560mg ml-1 and 2, 8mg ml-1 respectively. The MIC, MBC of AMPHOTRICIN B decreased to 1, 2mg ml-1 when 0.78 mg ml-1 of EXTRACT was added. Conclusion: AMPHOTRICIN B is a potent antifungal agent and MIC and MBC of E. platyloba is 780, 390 times less potent than AMPHOTRICIN B, but usage the AMPHOTRICIN B and E. platyloba EXTRACT in combination increased the potency of AMPHOTRICIN B which shows a synergistic effect.

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APA: Copy

MAHBOUBI, MOHADESEH, AVIZHGAN, M., DARABI, MAHDI, & KASAEIAN, NAZILA. (2009). ANTI CANDIDAL ACTIVITY OF ECHINOPHORA PLATYLOBA AGAINST CANDIDA ALBICANS AND COMPARISON WITH AMPHOTRICIN. JOURNAL OF MEDICINAL PLANTS, 8(30), 36-43. SID. https://sid.ir/paper/15597/en

Vancouver: Copy

MAHBOUBI MOHADESEH, AVIZHGAN M., DARABI MAHDI, KASAEIAN NAZILA. ANTI CANDIDAL ACTIVITY OF ECHINOPHORA PLATYLOBA AGAINST CANDIDA ALBICANS AND COMPARISON WITH AMPHOTRICIN. JOURNAL OF MEDICINAL PLANTS[Internet]. 2009;8(30):36-43. Available from: https://sid.ir/paper/15597/en

IEEE: Copy

MOHADESEH MAHBOUBI, M. AVIZHGAN, MAHDI DARABI, and NAZILA KASAEIAN, “ANTI CANDIDAL ACTIVITY OF ECHINOPHORA PLATYLOBA AGAINST CANDIDA ALBICANS AND COMPARISON WITH AMPHOTRICIN,” JOURNAL OF MEDICINAL PLANTS, vol. 8, no. 30, pp. 36–43, 2009, [Online]. Available: https://sid.ir/paper/15597/en

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