TREATMENT OF HYPERTROPHIC SCAR WITH INTRALESIONAL INJECTION OF BOTULINUM TOXIN A: A DOUBLE-BLIND, RANDOMIZED CONTROLLED CLINICAL TRIAL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

TAHERI AHMAD REZA; KHORASANI GHASEM ALI; FORGHANI SIAMAK; FATHI AFSHIN

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Dermatology and Cosmetics Year:2016 | Volume:7 | Issue:1 Page(s): 10-16

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,996

Download:

Cites:

Information Journal Paper

Title

TREATMENT OF HYPERTROPHIC SCAR WITH INTRALESIONAL INJECTION OF BOTULINUM TOXIN A: A DOUBLE-BLIND, RANDOMIZED CONTROLLED CLINICAL TRIAL

Author(s)

TAHERI AHMAD REZA | KHORASANI GHASEM ALI | FORGHANI SIAMAK | FATHI AFSHIN | Issue Writer Certificate

Keywords

BOTULINUM TOXIN AQ3

HYPERTROPHIC SCARQ1

INTRALESIONAL INJECTIONQ1

Abstract

Background and Aim: HYPERTROPHIC SCARs are highly resistant to the treatment and have a high recurrence rate. Affected patients suffer from aesthetic and functional complications, which may influence their quality of life. Nowadays, various therapeutic modalities have been used in the treatment of HYPERTROPHIC SCARs, but patients' problems remain because of high recurrence rate. This study evaluated the efficacy of INTRALESIONAL INJECTION of BOTULINUM TOXIN A in the treatment of HYPERTROPHIC SCAR lesions.Methods: This randomised controlled trial was performed during 2014 and 2015. Each patient’s lesion was randomly allocated in ine of the two arms of the study: one half of the lesion received monthly 8 IU/cm3 of 200 IU/ml intralesional BOTULINUM TOXIN A (Dysport, Ipsen Biopharma Ltd., UK) and the other half was injected with the same volume of normal saline. Injections were repeated three times. After 9 months, lesions were evaluated according to Vancouver scar scale.Results: Twenty-one patients with a mean age of 27.2 years completed the study. In the intervention the mean lesions` pigmentation scale decrease to 0.73, vascularity to 0.9 and pliability to 0.98 (P<0.01), but there was no significant change in lesions height (P=0.32).Conclusion: It seems that injection of BOTULINUM TOXIN A in HYPERTROPHIC SCAR lesions acts as useful adjuvant for other treatment methods.

Cites

No record.

References

No record.

Cite

APA: Copy

TAHERI, AHMAD REZA, KHORASANI, GHASEM ALI, FORGHANI, SIAMAK, & FATHI, AFSHIN. (2016). TREATMENT OF HYPERTROPHIC SCAR WITH INTRALESIONAL INJECTION OF BOTULINUM TOXIN A: A DOUBLE-BLIND, RANDOMIZED CONTROLLED CLINICAL TRIAL. DERMATOLOGY AND COSMETIC, 7(1), 10-16. SID. https://sid.ir/paper/157546/en

Vancouver: Copy

TAHERI AHMAD REZA, KHORASANI GHASEM ALI, FORGHANI SIAMAK, FATHI AFSHIN. TREATMENT OF HYPERTROPHIC SCAR WITH INTRALESIONAL INJECTION OF BOTULINUM TOXIN A: A DOUBLE-BLIND, RANDOMIZED CONTROLLED CLINICAL TRIAL. DERMATOLOGY AND COSMETIC[Internet]. 2016;7(1):10-16. Available from: https://sid.ir/paper/157546/en

IEEE: Copy

AHMAD REZA TAHERI, GHASEM ALI KHORASANI, SIAMAK FORGHANI, and AFSHIN FATHI, “TREATMENT OF HYPERTROPHIC SCAR WITH INTRALESIONAL INJECTION OF BOTULINUM TOXIN A: A DOUBLE-BLIND, RANDOMIZED CONTROLLED CLINICAL TRIAL,” DERMATOLOGY AND COSMETIC, vol. 7, no. 1, pp. 10–16, 2016, [Online]. Available: https://sid.ir/paper/157546/en

Related Journal Papers