COMPARING THE EFFECTS OF INDOMETACIN SUPPOSITORY WITH IM INJECTION PETHIDINE ON POST OPERATIVE PAIN AFTER CESAREAN SECTION

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ELIASI H.; HEYDARI M.; SHAHBEYGI S.

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Journal: Researcher Bulletin of Medical Sciences Year:2001 | Volume:5 | Issue:4 (20) Page(s): 347-352

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Title

COMPARING THE EFFECTS OF INDOMETACIN SUPPOSITORY WITH IM INJECTION PETHIDINE ON POST OPERATIVE PAIN AFTER CESAREAN SECTION

Author(s)

ELIASI H. | HEYDARI M. | SHAHBEYGI S. | Issue Writer Certificate

Keywords

INDOMETACINQ3

PETHIDINEQ3

POSTOPERATIVE PAINQ3

Abstract

The vast majority of people undergone operations each year have experienced POSTOPERATIVE PAIN of varying intensity. Regarding the wide usage of INDOMETACIN as a NSAID in such patients, this study has been conducted with the aim of comparing the effects of INDOMETACIN suppository with IM injection PETHIDINE on post operative pain after cesarean section in Mahdieh Hospital, 1999-2000. This double-blinded clinical trial has been conducted on 90 pregnant women undergone cesarean section through spinal anesthesia with sequential sampling. They were divided in two groups of case (INDOMETACIN supp.) and control (IM injection PETHIDINE). The case group has received 100 mg INDOMETACIN supp. and the other group was given 0.5 mg/kg PETHIDINE, 1.5 hours later after spinal anesthesia with marcain. Then, the-case group has received 100mg INDOMETACIN supp. 8 hrs later whereas the control group was given 0.5 mg/kg PETHIDINE PRN. The NRS (Numerical Rating Scales) pain scores were collected every 4 hrs for 16 hrs. Patients were distributed in three groups of; no pain (0), moderate pain (1-5), and severe pain (6-10). 84% of the patients using INDOMETACIN have experienced no to moderate pain in the first visit and the remaining 16% had severe pain, however, in the control group moderate and severe pain were recorded in 53 and 47% of the patients, respectively (p<0.0005). During the second visit, no or moderate pain was seen in 95.6% of the patients receiving INDOMETACIN and the remaining 4.4% had suffered severe pain, whereas in the control group moderate pain was recorded in 75.6% of the patients and the remaining 24.4% experienced severe pain (p<0.0005). Third visit has revealed the following results: in the case group 49% of the patients were painless and 51 % had moderate pain, but in the other group moderate pain has been recorded in 95.6% of the patients and the remaining 4.4% had severe pain. During the fourth visit 69% of the patients in the case group were painless and 31 % had moderate pain, but in the control group all the patients have suffered from moderate pain (p<0.00005). Out of bed time was significantly shorter in women who received indomethacin versus pethedine. In case of clockwise usage of INDOMETACIN, especially before post-operative pain return, it is strongly recommended in comparison with PRN usage of IM injection PETHIDINE due to its cost benefit and lack of opioids complications.

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APA: Copy

ELIASI, H., HEYDARI, M., & SHAHBEYGI, S.. (2001). COMPARING THE EFFECTS OF INDOMETACIN SUPPOSITORY WITH IM INJECTION PETHIDINE ON POST OPERATIVE PAIN AFTER CESAREAN SECTION. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 5(4 (20)), 347-352. SID. https://sid.ir/paper/18368/en

Vancouver: Copy

ELIASI H., HEYDARI M., SHAHBEYGI S.. COMPARING THE EFFECTS OF INDOMETACIN SUPPOSITORY WITH IM INJECTION PETHIDINE ON POST OPERATIVE PAIN AFTER CESAREAN SECTION. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2001;5(4 (20)):347-352. Available from: https://sid.ir/paper/18368/en

IEEE: Copy

H. ELIASI, M. HEYDARI, and S. SHAHBEYGI, “COMPARING THE EFFECTS OF INDOMETACIN SUPPOSITORY WITH IM INJECTION PETHIDINE ON POST OPERATIVE PAIN AFTER CESAREAN SECTION,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 5, no. 4 (20), pp. 347–352, 2001, [Online]. Available: https://sid.ir/paper/18368/en

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