IMPLANTATION OF OCTACALCIUM PHOSPHATE TO ENHANCE OSTEOGENSIS OF ALVEOLAR RIDGE DEFECT IN RAT MANDIBLE

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SARGOLZAEI AVAL F.; ARAB M.R.; SARANI SHIR AHMAD; SABERI E.A.

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Journal: Journal of Dental School Year:2007 | Volume:25 | Issue:2 (72) Page(s): 167-173

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Title

IMPLANTATION OF OCTACALCIUM PHOSPHATE TO ENHANCE OSTEOGENSIS OF ALVEOLAR RIDGE DEFECT IN RAT MANDIBLE

Author(s)

SARGOLZAEI AVAL F. | ARAB M.R. | SARANI SHIR AHMAD | SABERI E.A. | Issue Writer Certificate

Keywords

OCTACALCIUM PHOSPHATEQ3

NEW OSTEOGENESISQ3

ALVEOLAR RIDGEQ3

Abstract

Background and Aim: Reconstruction of craniofacial bone defects remains one of the most challenging problems encountered by maxillofacial surgeons. This study was designed to investigate the process of bone formation caused by implantation of OCTACALCIUM PHOSPHATE at mandibular ALVEOLAR RIDGE of rat.Methods & Materials: In this experimental animal study, 20 male Sprague Dawley rats were used. Synthetic OCTACALCIUM PHOSPHATE (OCP) was implanted into the bony defect measuring 3 mm in diameter and 2 mm in depth which was surgically created with a bur in the rat mandible. Bone formation at the ALVEOLAR RIDGE was examined histologically between I and 4 weeks after implantation.Result: Osteogenesis was initiated in the center of the defect between the OCP particles and multinucleated giant cells appeared on the implanted materials in 1 week. More apposition of new bone was observed on the implanted OCTACALCIUM PHOSPHATE in week 2. In addition to bone formation locally around the OCP particles, more apposition of new bone was observed near the defect margin in week 3. At week 4, the defect was almost completely filled with bone, which was in close contact with host bone and implanted OCP was surrounded by newly formed bone. In the control group, bone formation was observed only along and near the defect margin.Conclusion: OCTACALCIUM PHOSPHATE could be used to enhance atrophic ALVEOLAR RIDGE or for filling a tooth socket after extraction.

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References

THE EFFECT OF OCTACALCIUM PHOSPHATE (OCP) ON THE REPAIR OF PARIETAL BONE DEFECTS IN RATS

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APA: Copy

SARGOLZAEI AVAL, F., ARAB, M.R., SARANI, SHIR AHMAD, & SABERI, E.A.. (2007). IMPLANTATION OF OCTACALCIUM PHOSPHATE TO ENHANCE OSTEOGENSIS OF ALVEOLAR RIDGE DEFECT IN RAT MANDIBLE. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, 25(2 (72)), 167-173. SID. https://sid.ir/paper/21674/en

Vancouver: Copy

SARGOLZAEI AVAL F., ARAB M.R., SARANI SHIR AHMAD, SABERI E.A.. IMPLANTATION OF OCTACALCIUM PHOSPHATE TO ENHANCE OSTEOGENSIS OF ALVEOLAR RIDGE DEFECT IN RAT MANDIBLE. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE[Internet]. 2007;25(2 (72)):167-173. Available from: https://sid.ir/paper/21674/en

IEEE: Copy

F. SARGOLZAEI AVAL, M.R. ARAB, SHIR AHMAD SARANI, and E.A. SABERI, “IMPLANTATION OF OCTACALCIUM PHOSPHATE TO ENHANCE OSTEOGENSIS OF ALVEOLAR RIDGE DEFECT IN RAT MANDIBLE,” JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, vol. 25, no. 2 (72), pp. 167–173, 2007, [Online]. Available: https://sid.ir/paper/21674/en

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