MOLECULAR STUDY OF PER AND VEB GENES IS MULTIDRUG RESISTANT PSEUDOMONAS AEROGINOSA ISOLATED FROM CLINICAL SPECIMENS IN ISFAHAN/IRAN AND THEIR ANTIBIOTIC RESISTANCE PATTERNS

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FAZELI H.; FATAHI BAFGHI M.; FAGHRI M.; AKBARI R.

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Journal: Journal of Kerman University of Medical Sciences Year:2012 | Volume:19 | Issue:4 Page(s): 345-353

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Title

MOLECULAR STUDY OF PER AND VEB GENES IS MULTIDRUG RESISTANT PSEUDOMONAS AEROGINOSA ISOLATED FROM CLINICAL SPECIMENS IN ISFAHAN/IRAN AND THEIR ANTIBIOTIC RESISTANCE PATTERNS

Author(s)

FAZELI H. | FATAHI BAFGHI M. | FAGHRI M. | AKBARI R. | Issue Writer Certificate

Keywords

BETA-LACTAMASEQ2

PSEUDOMONAS AERUGINOSAQ2

PERQ2

VEBQ2

Abstract

Background & Aims: Duo to clinical use of antibiotics, PSEUDOMONAS AERUGINOSA strains with multiple drugs resistance have significantly increased throughout the world. Beta lactamase production is one of the Mechanisms involved in resistance to PSEUDOMONAS AERUGINOSA resulting in many problems in the treatment of infections caused by this bacterium. The aim of this study was molecular analysis of PER and VEB genes in Pseudomonas with multiple resistance isolated from clinical samples in Isfahan/Iran.Methods: In whole, 98 isolates of PSEUDOMONAS AERUGINOSA from various clinical specimens were identified by biochemical tests and the antibiotic susceptibility of the identified strains were determined using Kirby-Bauer method. PCR was PERformed on the samples to evaluate the presence or absence of PER and VEB genes. Results: Among 98 strains of PSEUDOMONAS AERUGINOSA, 73 samples (73%) were multiple drugs resistant and all of them were cefotaxime, cefepime and ceftazidime resistant. Prevalence of PER and VEB genes were respectively 5 (6.84%) and 8 (10.9%). Conclusion: Considering high prevalence of multi-drug resistant Pseudomonas aeroginosa, it is essential to reduce these pathogens in hospitals through controlling PER and VEB genes transfer.

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APA: Copy

FAZELI, H., FATAHI BAFGHI, M., FAGHRI, M., & AKBARI, R.. (2012). MOLECULAR STUDY OF PER AND VEB GENES IS MULTIDRUG RESISTANT PSEUDOMONAS AEROGINOSA ISOLATED FROM CLINICAL SPECIMENS IN ISFAHAN/IRAN AND THEIR ANTIBIOTIC RESISTANCE PATTERNS. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, 19(4), 345-353. SID. https://sid.ir/paper/26/en

Vancouver: Copy

FAZELI H., FATAHI BAFGHI M., FAGHRI M., AKBARI R.. MOLECULAR STUDY OF PER AND VEB GENES IS MULTIDRUG RESISTANT PSEUDOMONAS AEROGINOSA ISOLATED FROM CLINICAL SPECIMENS IN ISFAHAN/IRAN AND THEIR ANTIBIOTIC RESISTANCE PATTERNS. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;19(4):345-353. Available from: https://sid.ir/paper/26/en

IEEE: Copy

H. FAZELI, M. FATAHI BAFGHI, M. FAGHRI, and R. AKBARI, “MOLECULAR STUDY OF PER AND VEB GENES IS MULTIDRUG RESISTANT PSEUDOMONAS AEROGINOSA ISOLATED FROM CLINICAL SPECIMENS IN ISFAHAN/IRAN AND THEIR ANTIBIOTIC RESISTANCE PATTERNS,” JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, vol. 19, no. 4, pp. 345–353, 2012, [Online]. Available: https://sid.ir/paper/26/en

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