EFFECTS OF UNCONTROLLED STRESS IN PREGNANT RATS ON THE SIZE OF FETUS THYMUS

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MIRDAMADIAN Z.S.; SAHRAEI HEDAYAT; ESFANDIARI BEHNAZ; BAHADORAN H.

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Journal: KOWSAR MEDICAL JOURNAL Year:2008 | Volume:13 | Issue:1 Page(s): 9-16

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Title

EFFECTS OF UNCONTROLLED STRESS IN PREGNANT RATS ON THE SIZE OF FETUS THYMUS

Author(s)

MIRDAMADIAN Z.S. | SAHRAEI HEDAYAT | ESFANDIARI BEHNAZ | BAHADORAN H. | Issue Writer Certificate

Keywords

IMMOBILIZATION STRESSQ3

NOISE STRESSQ3

THYMUSQ3

RATQ3

Abstract

Introduction: stress is a wide range word with abroad meaning, which could be considered as any cause of changes in internal milieu. Previous studies have consisted the role of stress in some disease including diabetes mellitus.Aim: relationship between gestational life stress and the THYMUS size was studied in this experiment.Material and Methods: 21 female Wistar RATs (w: 250-300) were used in this experiment. Animals were divided in to three groups (control: 7, NOISE STRESS: 7, IMMOBILIZATION STRESS: 7). Experimental groups after mating with male RATs were exposed to their, relative stress (15 min /day; 15 consecutive days). On 19 the embryonic day, all pregnant RATs were anesthetized by ether and the embryos were pulled out surgically .the embryos fixed in buen fixative solution for 48 hours.After this time, the weight and length of the embryos were calculation by digital balance and cullies respectively. The embryos then were prepared for histological possessing and H&E staining .results were evaluated by mean MOTIC software and optic microscope.Results: our data showed that the embryos weight and length were not statistically different in all groups. In contrast, the THYMUS size in experiment groups was significantly reduced with respect to the control.Discussion: although the uncontrolled stress did not affect the weight and length of the embryos, reduction of THYMUS size could be considered as a good reason for embryos affective from gestational stress. Because of the reduction in THYMUS size, it could be predicted that the embryos experience some immune problems after birth.

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APA: Copy

MIRDAMADIAN, Z.S., SAHRAEI, HEDAYAT, ESFANDIARI, BEHNAZ, & BAHADORAN, H.. (2008). EFFECTS OF UNCONTROLLED STRESS IN PREGNANT RATS ON THE SIZE OF FETUS THYMUS. KOWSAR MEDICAL JOURNAL, 13(1), 9-16. SID. https://sid.ir/paper/32697/en

Vancouver: Copy

MIRDAMADIAN Z.S., SAHRAEI HEDAYAT, ESFANDIARI BEHNAZ, BAHADORAN H.. EFFECTS OF UNCONTROLLED STRESS IN PREGNANT RATS ON THE SIZE OF FETUS THYMUS. KOWSAR MEDICAL JOURNAL[Internet]. 2008;13(1):9-16. Available from: https://sid.ir/paper/32697/en

IEEE: Copy

Z.S. MIRDAMADIAN, HEDAYAT SAHRAEI, BEHNAZ ESFANDIARI, and H. BAHADORAN, “EFFECTS OF UNCONTROLLED STRESS IN PREGNANT RATS ON THE SIZE OF FETUS THYMUS,” KOWSAR MEDICAL JOURNAL, vol. 13, no. 1, pp. 9–16, 2008, [Online]. Available: https://sid.ir/paper/32697/en

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