N-ACETYL CYSTEINE EFFECT ON LIFE QUALITY OF MORPHINE ADDICTS IN TREATMENT PERIOD: A PILOTE STUDY

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SHOHRATI M.; ALMASI V.; SHAJIEI A.; NEKOUHESH L.; NAJAFIAN B.; NAGHIZADEH M.M.

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Journal: KOWSAR MEDICAL JOURNAL Year:2009 | Volume:13 | Issue:4 Page(s): 297-301

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Title

N-ACETYL CYSTEINE EFFECT ON LIFE QUALITY OF MORPHINE ADDICTS IN TREATMENT PERIOD: A PILOTE STUDY

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Keywords

N-ACETYL CYSTEINEQ3

QUALITY OF LIFEQ2

ADDICTIONQ3

Abstract

AIMS: The purpose of this study is to determine N-ACETYL CYSTEINE effect on life quality of addicts who are in treatment period camparing with placebo.METHODS: In this double blind, placebo control clinical trial study, two groups (drug and placebo; each 20 people) among the persons who respect for treatment of their opium ADDICTION in treatment center in Tehran were selected with systematic sampling method. 1200 mg/day drug and placebo were administered to drug and placebo groups, respectively, for 45 days. QUALITY OF LIFE was evaluated with SF-36 standard questionnaire, before and after drug administration. Finally, the results were analyzed with Mann-Whitney and Wilcoxon tests and SPSS software.RESULTS: SF-36 total point mean, before intervention was 44±11 in drug group and 40±9 in placebo group that there was no significant relation before intervention (p>0.05). After intervention, SF-36 total point mean in drug and placebo groups were 78±7 and 70±9, respectively, that there was significant relation after intervention between SF-36 total point in Mann-Withney test (p=0.018).CONCLUSION: N-ACETYL CYSTEINE has significant effect on improving of life quality in addicts in their ADDICTION treatment period.

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APA: Copy

SHOHRATI, M., ALMASI, V., SHAJIEI, A., NEKOUHESH, L., NAJAFIAN, B., & NAGHIZADEH, M.M.. (2009). N-ACETYL CYSTEINE EFFECT ON LIFE QUALITY OF MORPHINE ADDICTS IN TREATMENT PERIOD: A PILOTE STUDY. KOWSAR MEDICAL JOURNAL, 13(4), 297-301. SID. https://sid.ir/paper/32884/en

Vancouver: Copy

SHOHRATI M., ALMASI V., SHAJIEI A., NEKOUHESH L., NAJAFIAN B., NAGHIZADEH M.M.. N-ACETYL CYSTEINE EFFECT ON LIFE QUALITY OF MORPHINE ADDICTS IN TREATMENT PERIOD: A PILOTE STUDY. KOWSAR MEDICAL JOURNAL[Internet]. 2009;13(4):297-301. Available from: https://sid.ir/paper/32884/en

IEEE: Copy

M. SHOHRATI, V. ALMASI, A. SHAJIEI, L. NEKOUHESH, B. NAJAFIAN, and M.M. NAGHIZADEH, “N-ACETYL CYSTEINE EFFECT ON LIFE QUALITY OF MORPHINE ADDICTS IN TREATMENT PERIOD: A PILOTE STUDY,” KOWSAR MEDICAL JOURNAL, vol. 13, no. 4, pp. 297–301, 2009, [Online]. Available: https://sid.ir/paper/32884/en

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