HEPATIC LIPASE C-514T POLYMORPHISM AND ITS ASSOCIATION WITH HDL-C LEVEL IN TEHRAN

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DANESHPOUR M.A.S.; HEDAYATI S.M.; AZIZI F.

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Journal: KOWSAR MEDICAL JOURNAL Year:2005 | Volume:10 | Issue:2 Page(s): 135-142

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Information Journal Paper

Title

HEPATIC LIPASE C-514T POLYMORPHISM AND ITS ASSOCIATION WITH HDL-C LEVEL IN TEHRAN

Author(s)

DANESHPOUR M.A.S. | HEDAYATI S.M. | AZIZI F. | Issue Writer Certificate

Keywords

LIPCQ4

HDL-CQ4

POLYMORPHISMQ2

NLAIIIQ4

TEHRANQ2

Abstract

Objective: The aim of this study is to evaluate a significant relationship between C-514T POLYMORPHISM in LIPC gene and C-514T POLYMORPHISM in TEHRAN papulation. Material and Methods: Serum levels of glucose, triglyceride, total cholesterol and HDL-C were measured in 258 men and 287 women. A segment of the gene mentioned was amplified with PCR and the POLYMORPHISM with RFLP-NlaIII was revealed. Results: The T allele frequency was 0.164 in men and 0.144 in women. A significant relationship between HDL-C levels and C-514T POLYMORPHISM was not found even after adjusting for age, BMI and blood pressure. Conclusion: Our experiment concludes that C-514T POLYMORPHISM in TEHRAN's population is similar to other caucasians. However, we could not find any significant statistical relationship between this POLYMORPHISM with low serum HDL-C concentration in this population.

Cites

COMPARISON OF PRECIPITATION AND DIRECT METHODS FOR HDL-C ASSAY

References

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APA: Copy

DANESHPOUR, M.A.S., HEDAYATI, S.M., & AZIZI, F.. (2005). HEPATIC LIPASE C-514T POLYMORPHISM AND ITS ASSOCIATION WITH HDL-C LEVEL IN TEHRAN. KOWSAR MEDICAL JOURNAL, 10(2), 135-142. SID. https://sid.ir/paper/32962/en

Vancouver: Copy

DANESHPOUR M.A.S., HEDAYATI S.M., AZIZI F.. HEPATIC LIPASE C-514T POLYMORPHISM AND ITS ASSOCIATION WITH HDL-C LEVEL IN TEHRAN. KOWSAR MEDICAL JOURNAL[Internet]. 2005;10(2):135-142. Available from: https://sid.ir/paper/32962/en

IEEE: Copy

M.A.S. DANESHPOUR, S.M. HEDAYATI, and F. AZIZI, “HEPATIC LIPASE C-514T POLYMORPHISM AND ITS ASSOCIATION WITH HDL-C LEVEL IN TEHRAN,” KOWSAR MEDICAL JOURNAL, vol. 10, no. 2, pp. 135–142, 2005, [Online]. Available: https://sid.ir/paper/32962/en

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