EFFECT OF WATER COFFEE EXTRACT ON KIDNEY VOLUME (A STEREOLOGICAL STUDY)

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DEHGHANI F.; DEZFOULIAN A.R.; PANJEH SHAHIN M.R.

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Journal: IRANIAN SOUTH MEDICAL JOURNAL (ISMJ) Year:2013 | Volume:16 | Issue:3 Page(s): 207-214

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Title

EFFECT OF WATER COFFEE EXTRACT ON KIDNEY VOLUME (A STEREOLOGICAL STUDY)

Author(s)

DEHGHANI F. | DEZFOULIAN A.R. | PANJEH SHAHIN M.R. | Issue Writer Certificate

Keywords

COFFEINEQ2

STEREOLOGYQ3

KIDNEYQ2

GLOMERULEQ3

Abstract

Background: Coffee is a traditional drinking used by most of the people around the world. Overuse of coffee leads to many side effects on body. In this study, the effect of different doses of coffee extract on KIDNEY volume was studied by the stereological method.Material and Methods: Sixty spragu-dawley male rats were divided into 6 groups. Control group was given tap water (0.5 ml) and experimental groups were given coffee extract orally for 14 days with doses (0.125, 0.25, 0.5, 1, 1.5gr/kg) with the same volume of control group. Then rats were anesthetized (with ether), sacrificed and their right KIDNEYs were removed, fixed, tissue processed and stained with H& E. The 5 mm slides were studied by Cavalieri principle.Results: Higher doses of water coffee extract were associated with decreased KIDNEY volume and volumes of GLOMERULEs but in lower doses it increased related to control group.Conclusion: It seems that, high doses of coffee has side effect on KIDNEYand reduces volume of KIDNEY and its GLOMERULEs. However further studies are required to confirm this research.

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APA: Copy

DEHGHANI, F., DEZFOULIAN, A.R., & PANJEH SHAHIN, M.R.. (2013). EFFECT OF WATER COFFEE EXTRACT ON KIDNEY VOLUME (A STEREOLOGICAL STUDY). IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 16(3), 207-214. SID. https://sid.ir/paper/33633/en

Vancouver: Copy

DEHGHANI F., DEZFOULIAN A.R., PANJEH SHAHIN M.R.. EFFECT OF WATER COFFEE EXTRACT ON KIDNEY VOLUME (A STEREOLOGICAL STUDY). IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2013;16(3):207-214. Available from: https://sid.ir/paper/33633/en

IEEE: Copy

F. DEHGHANI, A.R. DEZFOULIAN, and M.R. PANJEH SHAHIN, “EFFECT OF WATER COFFEE EXTRACT ON KIDNEY VOLUME (A STEREOLOGICAL STUDY),” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 16, no. 3, pp. 207–214, 2013, [Online]. Available: https://sid.ir/paper/33633/en

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